Radiographic identification of visceroptosis in hypermobile Ehlers-Danlos syndrome patients with functional gastrointestinal symptoms compared to healthy subjects.

IF 3 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Clinical and Translational Gastroenterology Pub Date : 2025-03-03 DOI:10.14309/ctg.0000000000000834

Yin Chan, Bianca W Chang, Amrit K Kaboj, Yaniv Raphael, Richard Sukov, Ali Rezaie

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引用次数: 0

Abstract

Introduction: Visceroptosis is a potential cause of gastrointestinal symptoms in hypermobile Ehlers-Danlos syndrome (hEDS).

Methods: We systematically examined the prolapse of abdominal organs below their natural supine position (visceroptosis) during upright small bowel barium study in healthy and hEDS subjects with irritable bowel syndrome.

Results: Comparison of age- and sex-matched healthy (n=20) and hEDS (n=10) subjects did not show any significant difference in dynamic movement of the viscera. Subgroup analysis did not demonstrate any correlation between the degree of prolapse, clinical symptoms, and hypermobility clinical (Beighton) scores. The interobserver reliability for 3 out the 4 anatomical landmarks showed 'moderate' or 'good' correlation based on their interclass correlation coefficients.

Discussion: hEDS patients do not appear to have a significantly increased incidence of visceroptosis.

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来源期刊

Clinical and Translational Gastroenterology GASTROENTEROLOGY & HEPATOLOGY-

CiteScore

7.00

自引率

0.00%

发文量

114

审稿时长

16 weeks

期刊介绍： Clinical and Translational Gastroenterology (CTG), published on behalf of the American College of Gastroenterology (ACG), is a peer-reviewed open access online journal dedicated to innovative clinical work in the field of gastroenterology and hepatology. CTG hopes to fulfill an unmet need for clinicians and scientists by welcoming novel cohort studies, early-phase clinical trials, qualitative and quantitative epidemiologic research, hypothesis-generating research, studies of novel mechanisms and methodologies including public health interventions, and integration of approaches across organs and disciplines. CTG also welcomes hypothesis-generating small studies, methods papers, and translational research with clear applications to human physiology or disease. Colon and small bowel Endoscopy and novel diagnostics Esophagus Functional GI disorders Immunology of the GI tract Microbiology of the GI tract Inflammatory bowel disease Pancreas and biliary tract Liver Pathology Pediatrics Preventative medicine Nutrition/obesity Stomach.