Parenteral nutritional support in surgical patients: expert consensus statements regarding intravenous lipid emulsions containing omega-3 fatty acids.

IF 4 2区 农林科学 Q2 NUTRITION & DIETETICS Frontiers in Nutrition Pub Date : 2025-02-17 eCollection Date: 2025-01-01 DOI:10.3389/fnut.2025.1546089
Robert G Martindale, David C Evans, Dan Waitzberg, Malissa Warren, Manpreet S Mundi, Stanislaw Klek, Paul E Wischmeyer, Martin D Rosenthal
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Abstract

Objectives: The International Lipids in Parenteral Nutrition (PN) Summit was convened to offer practical guidance and expert consensus opinion regarding the use of intravenous lipid emulsions (ILEs) in various clinical settings. Herein, we briefly review aspects from this summit that are of particular importance for surgical/hospitalized patients.

Methods: Summit participants identified and discussed new evidence, data, and analyses, that potentially influence the benefits and risks of ILEs in PN or their use in clinical practice. The summit meeting consisted of expert presentations that assessed recent clinical data and best practice, followed by periodic panel discussions to formulate consensus statements. Consensus statements were voted on, anonymously, by the meeting attendees.

Results: This review briefly summarizes the rationale for considering ILE choice as a central component of any PN strategy for surgical/hospitalized patients. Thereafter, special patient populations are considered, such as surgery-related intestinal failure, major trauma, and those with chronic critical illnesses. Expert consensus statements are also provided to help bridge the gaps between evidence and clinical practice, hence complementing formal PN societal guideline recommendations.

Conclusion: The choice of ILE in PN, particularly those containing fish oil, can play a vital role in improving outcomes for surgical patients.

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外科病人的肠外营养支持:关于含有omega-3脂肪酸的静脉脂质乳剂的专家共识声明。
目的:召开国际肠外营养脂质(PN)峰会,为在各种临床环境中使用静脉内脂质乳剂(ILEs)提供实用指导和专家共识意见。在此,我们简要回顾了本次峰会对外科/住院患者特别重要的方面。方法:峰会参与者确定并讨论了新的证据、数据和分析,这些证据、数据和分析可能会影响在PN中应用ILEs的益处和风险,或影响其在临床实践中的应用。首脑会议包括评估最近临床数据和最佳做法的专家报告,随后是定期小组讨论,以制定共识声明。与会者对共识声明进行了匿名投票。结果:本综述简要总结了将ILE选择作为外科/住院患者任何PN策略的核心组成部分的基本原理。此后,特殊的患者群体被考虑,如手术相关的肠衰竭,重大创伤,和那些患有慢性危重疾病。专家共识声明也提供,以帮助弥合证据和临床实践之间的差距,从而补充正式的PN社会指南建议。结论:在PN患者中选择ILE,特别是那些含有鱼油的ILE,对改善手术患者的预后起着至关重要的作用。
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来源期刊
Frontiers in Nutrition
Frontiers in Nutrition Agricultural and Biological Sciences-Food Science
CiteScore
5.20
自引率
8.00%
发文量
2891
审稿时长
12 weeks
期刊介绍: No subject pertains more to human life than nutrition. The aim of Frontiers in Nutrition is to integrate major scientific disciplines in this vast field in order to address the most relevant and pertinent questions and developments. Our ambition is to create an integrated podium based on original research, clinical trials, and contemporary reviews to build a reputable knowledge forum in the domains of human health, dietary behaviors, agronomy & 21st century food science. Through the recognized open-access Frontiers platform we welcome manuscripts to our dedicated sections relating to different areas in the field of nutrition with a focus on human health. Specialty sections in Frontiers in Nutrition include, for example, Clinical Nutrition, Nutrition & Sustainable Diets, Nutrition and Food Science Technology, Nutrition Methodology, Sport & Exercise Nutrition, Food Chemistry, and Nutritional Immunology. Based on the publication of rigorous scientific research, we thrive to achieve a visible impact on the global nutrition agenda addressing the grand challenges of our time, including obesity, malnutrition, hunger, food waste, sustainability and consumer health.
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