Prashant V. Rajan MD , Joshua Eisenberg MD , Stephen Selverian MD , Richard Wawrose MD , Sangwook Tim Yoon MD, PhD
{"title":"The cost-effectiveness of physical therapy versus laminectomy for lumbar spinal stenosis: a Markov decision analysis","authors":"Prashant V. Rajan MD , Joshua Eisenberg MD , Stephen Selverian MD , Richard Wawrose MD , Sangwook Tim Yoon MD, PhD","doi":"10.1016/j.spinee.2025.02.008","DOIUrl":null,"url":null,"abstract":"<div><h3>BACKGROUND CONTEXT</h3><div>Physical therapy is often utilized as a nonoperative modality for the treatment of lumbar stenosis, oftentimes a prerequisite for insurance approval for surgery.</div></div><div><h3>PURPOSE</h3><div>The goal of our study was to evaluate the relative cost-effectiveness of physical therapy as compared to a hospital-based or inpatient single-level lumbar laminectomy from the outset for lumbar stenosis.</div></div><div><h3>STUDY DESIGN/SETTING</h3><div>Cost-effectiveness analysis, Markov model simulation.</div></div><div><h3>PATIENT SAMPLE</h3><div>We developed a Markov model to analyze the baseline case: a 55-year-old patient with symptomatic lumbar stenosis undergoing physical therapy versus lumbar laminectomy from outset.</div></div><div><h3>OUTCOME MEASURES</h3><div>Model outcome measures were total quality-adjusted life years (QALYs) and costs, organized into incremental cost-effectiveness ratios (ICERs). ICERs were evaluated against willingness-to-pay thresholds (WTP) of $50,000 and $100,000.</div></div><div><h3>METHODS</h3><div>Transition probabilities were derived from the literature. Univariate and bivariate sensitivity analyses were performed as well as a probabilistic analysis varying several sensitive variables over distributions through 10,000 different simulations. Both healthcare payer and societal perspectives were included.</div></div><div><h3>RESULTS</h3><div>From healthcare payer perspective, laminectomy from outset produced higher QALYs (12.11 vs 11.87) at lower total cost ($15,735 vs $16,877) and was thus the dominant treatment. From societal perspective, physical therapy generated lower costs ($32,007) compared to laminectomy ($32,368). With an ICER of $1,485 per QALY for laminectomy which was below the WTP thresholds. The results were not sensitive to the procedural costs of laminectomy and physical therapy. In probabilistic sensitivity analysis, virtually all iterations found laminectomy from outset to be cost-effective over physical therapy across all WTP thresholds.</div></div><div><h3>CONCLUSIONS</h3><div>Our cost-effectiveness analysis showed laminectomy to be the preferred treatment strategy from the outset for symptomatic lumbar stenosis from both healthcare payer and societal perspectives. These findings highlight the need for further study into the effectiveness and cost-efficiency of physical therapy to validate these model-based findings and explore ways to optimize the management of lumbar stenosis.</div></div>","PeriodicalId":49484,"journal":{"name":"Spine Journal","volume":"25 8","pages":"Pages 1608-1617"},"PeriodicalIF":4.7000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Spine Journal","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1529943025001214","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
BACKGROUND CONTEXT
Physical therapy is often utilized as a nonoperative modality for the treatment of lumbar stenosis, oftentimes a prerequisite for insurance approval for surgery.
PURPOSE
The goal of our study was to evaluate the relative cost-effectiveness of physical therapy as compared to a hospital-based or inpatient single-level lumbar laminectomy from the outset for lumbar stenosis.
STUDY DESIGN/SETTING
Cost-effectiveness analysis, Markov model simulation.
PATIENT SAMPLE
We developed a Markov model to analyze the baseline case: a 55-year-old patient with symptomatic lumbar stenosis undergoing physical therapy versus lumbar laminectomy from outset.
OUTCOME MEASURES
Model outcome measures were total quality-adjusted life years (QALYs) and costs, organized into incremental cost-effectiveness ratios (ICERs). ICERs were evaluated against willingness-to-pay thresholds (WTP) of $50,000 and $100,000.
METHODS
Transition probabilities were derived from the literature. Univariate and bivariate sensitivity analyses were performed as well as a probabilistic analysis varying several sensitive variables over distributions through 10,000 different simulations. Both healthcare payer and societal perspectives were included.
RESULTS
From healthcare payer perspective, laminectomy from outset produced higher QALYs (12.11 vs 11.87) at lower total cost ($15,735 vs $16,877) and was thus the dominant treatment. From societal perspective, physical therapy generated lower costs ($32,007) compared to laminectomy ($32,368). With an ICER of $1,485 per QALY for laminectomy which was below the WTP thresholds. The results were not sensitive to the procedural costs of laminectomy and physical therapy. In probabilistic sensitivity analysis, virtually all iterations found laminectomy from outset to be cost-effective over physical therapy across all WTP thresholds.
CONCLUSIONS
Our cost-effectiveness analysis showed laminectomy to be the preferred treatment strategy from the outset for symptomatic lumbar stenosis from both healthcare payer and societal perspectives. These findings highlight the need for further study into the effectiveness and cost-efficiency of physical therapy to validate these model-based findings and explore ways to optimize the management of lumbar stenosis.
期刊介绍:
The Spine Journal, the official journal of the North American Spine Society, is an international and multidisciplinary journal that publishes original, peer-reviewed articles on research and treatment related to the spine and spine care, including basic science and clinical investigations. It is a condition of publication that manuscripts submitted to The Spine Journal have not been published, and will not be simultaneously submitted or published elsewhere. The Spine Journal also publishes major reviews of specific topics by acknowledged authorities, technical notes, teaching editorials, and other special features, Letters to the Editor-in-Chief are encouraged.