Effectiveness and predictive factors of nitrous oxide and oxygen inhalation sedation for paediatric dental procedures: a retrospective cohort study of Thai children.

IF 2.3 Q2 DENTISTRY, ORAL SURGERY & MEDICINE European Archives of Paediatric Dentistry Pub Date : 2025-03-03 DOI:10.1007/s40368-025-01013-w
P Poonyarit, N Chaipattanawan, C Manmontri, P Chompu-Inwai, A Nirunsittirat, P Phinyo
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引用次数: 0

Abstract

Purpose: To investigate the effectiveness and predictive factors of nitrous oxide and oxygen inhalation sedation (NOIS) in Thai paediatric dental patients.

Methods: A retrospective chart review of children receiving dental treatments under NOIS between March 2022 and August 2024 was conducted. A sedation session was evaluated as effective when the Overall Houpt Behaviour Rating Scale was greater than or equal to 4 and there were no acute adverse events from NOIS during or within 24 h of sedation. Predictive factors were assessed using the Poisson regression with robust error variance and generalised estimating equations.

Results: A total of 224 sedation sessions from 134 Thai patients aged 3-12 years were included. Of these sessions, 86.2% were considered effective. In the multivariable analysis, previous NOIS experience and the child's preoperative anxiety level were associated with the effectiveness of NOIS. The risk ratio for effective sedation was 13% higher for children with prior NOIS experience compared to those undergoing NOIS for the first time (RR: 1.13, 95% CI 1.02-1.25, p value < 0.05). In addition, the risk ratio for effective sedation in non-anxious children was 41% higher than for extremely anxious children (RR: 1.41, 95% CI 1.07-1.86, p value < 0.05).

Conclusion: NOIS is safe and effective for dental treatment in Thai children, with minimal adverse events. Its effectiveness is particularly pronounced in children who have prior experience with NOIS and present as non-anxious.

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来源期刊
European Archives of Paediatric Dentistry
European Archives of Paediatric Dentistry DENTISTRY, ORAL SURGERY & MEDICINE-
CiteScore
4.40
自引率
9.10%
发文量
81
期刊介绍: The aim and scope of European Archives of Paediatric Dentistry (EAPD) is to promote research in all aspects of dentistry for children, including interceptive orthodontics and studies on children and young adults with special needs. The EAPD focuses on the publication and critical evaluation of clinical and basic science research related to children. The EAPD will consider clinical case series reports, followed by the relevant literature review, only where there are new and important findings of interest to Paediatric Dentistry and where details of techniques or treatment carried out and the success of such approaches are given.
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