{"title":"18F-FDG PET/CT Identified Rectal Malignancy Earlier Than 68Ga-FAPI PET/CT.","authors":"Hui Wang, Minggang Su","doi":"10.1097/RLU.0000000000005800","DOIUrl":null,"url":null,"abstract":"<p><p>A 69-year-old man with esophageal cancer underwent dual-tracer PET/CT using 18F-FDG and 68Ga-FAPI during his treatment. At baseline, neither scan showed abnormal uptake in the rectum. Three months later, an interim 18F-FDG PET/CT revealed focal uptake in the rectum, while the 68Ga-FAPI PET/CT showed no abnormal findings. Seventeen months later, he received a third dual-tracer PET/CT for surveillance. Both 18F-FDG and 68Ga-FAPI PET/CT detected abnormal activity in the same area of the rectum. The lesion was later confirmed as adenocarcinoma by histopathology after surgery. Our case demonstrated the 18F-FDG PET/CT could identify the rectal malignancy before 68Ga-FAPI PET/CT.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":""},"PeriodicalIF":9.6000,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Nuclear Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/RLU.0000000000005800","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0
Abstract
A 69-year-old man with esophageal cancer underwent dual-tracer PET/CT using 18F-FDG and 68Ga-FAPI during his treatment. At baseline, neither scan showed abnormal uptake in the rectum. Three months later, an interim 18F-FDG PET/CT revealed focal uptake in the rectum, while the 68Ga-FAPI PET/CT showed no abnormal findings. Seventeen months later, he received a third dual-tracer PET/CT for surveillance. Both 18F-FDG and 68Ga-FAPI PET/CT detected abnormal activity in the same area of the rectum. The lesion was later confirmed as adenocarcinoma by histopathology after surgery. Our case demonstrated the 18F-FDG PET/CT could identify the rectal malignancy before 68Ga-FAPI PET/CT.
期刊介绍：
Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty.
Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.
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