TingYue Wen , YuChan Chen , JiaXi Li , HongXin Liu , WeiMin Zhang , XiaoXia Gao
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引用次数: 0
Abstract
Two new cytosporin derivatives, cytosporin Y4 (1) and cytosporin Y5 (2), together with seven known compounds (3–9) were isolated from Eutypella scoparia FS716, a fungus from the deep-sea sediment in South China Sea. The chemical structures of compounds 1 and 2 were established by 1D, 2D NMR, HRESIMIS, IR and UV spectroscopic data analyses. All the isolated compounds were evaluated for cytotoxic and anti-inflammatory activities. As a result, compounds 3–6, 8 and 9 showed significant anti-inflammatory activities.
期刊介绍：
Phytochemistry Letters invites rapid communications on all aspects of natural product research including:
• Structural elucidation of natural products
• Analytical evaluation of herbal medicines
• Clinical efficacy, safety and pharmacovigilance of herbal medicines
• Natural product biosynthesis
• Natural product synthesis and chemical modification
• Natural product metabolism
• Chemical ecology
• Biotechnology
• Bioassay-guided isolation
• Pharmacognosy
• Pharmacology of natural products
• Metabolomics
• Ethnobotany and traditional usage
• Genetics of natural products
Manuscripts that detail the isolation of just one new compound are not substantial enough to be sent out of review and are out of scope. Furthermore, where pharmacology has been performed on one new compound to increase the amount of novel data, the pharmacology must be substantial and/or related to the medicinal use of the producing organism.
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