A Case of Bilateral Irreversible Loss of Vision in a Young Child Due to Mumps Retinitis.

IF 2 4区 医学 Q2 OPHTHALMOLOGY Ocular Immunology and Inflammation Pub Date : 2025-09-01 Epub Date: 2025-03-06 DOI:10.1080/09273948.2025.2476062
Vivek B Wani, Deepashri Mutalik, Padmamalini Mahendradas, Mounesh Patil
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Abstract

Purpose: To describe a case of severe visual loss due to bilateral retinitis after mumps fever in a young child.

Methods: Observational case report.

Case report: A five-year-old boy presented with bilateral blindness 2 days after suffering from fever and parotid swelling. His examination showed vision of only perception of light, grade 2 anterior chamber activity, outer retinal necrosis involving whole retina with frosted branch angiitis like picture, inferior retinal detachment and few retinal hemorrhages in both eyes. His optical coherence tomography of retina showed diffuse thickening of the retina, subfoveal fluid and subretinal hypereflective material (SHRM) at the posterior pole with diffuse disruption of EZ and external limiting membrane (ELM). The serological test was positive for IgG and IgM antibodies against mumps virus. He did not respond to intravenous methylprednisolone, oral valganciclovir, hyperbaric oxygen and plasmapheresis. He developed foveal thinning, loss of external limiting membrane, ellipsoid zone and retinal pigment epithelial signals on optical coherence tomography with final vision of perception of light only.

Conclusions: Mumps retinitis is rare and can result in severe visual loss. The unique findings in our case were exudative retinal detachment, subretinal fluid and hyperreflective material at the posterior pole.

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小儿腮腺炎性视网膜炎所致双侧不可逆视力丧失一例。
目的:描述一个病例严重的视力丧失,由于双侧视网膜炎后腮腺炎热在一个年幼的孩子。方法:观察性病例报告。病例报告:一名五岁男童在发烧及腮腺肿大2天后出现双侧失明。检查显示视力仅能感知光,前房2级活动,视网膜外坏死累及整个视网膜并伴有霜状支血管炎,下视网膜脱离,双眼少量视网膜出血。他的视网膜光学相干断层扫描显示视网膜弥漫性增厚,后极有中央凹下液和视网膜下高反射物质(SHRM), EZ和外限制膜(ELM)弥漫性破坏。血清抗腮腺炎病毒IgG和IgM抗体阳性。静脉注射甲基强的松龙、口服缬更昔洛韦、高压氧和血浆置换治疗均无反应。他在光学相干断层扫描上表现为中央凹变薄、外限制膜丧失、椭球带和视网膜色素上皮信号,最终仅能感知光。结论:腮腺炎视网膜炎是罕见的,可导致严重的视力丧失。我们病例的独特发现是渗出性视网膜脱离,视网膜下液体和后极高反射物质。
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来源期刊
CiteScore
6.20
自引率
15.20%
发文量
285
审稿时长
6-12 weeks
期刊介绍: Ocular Immunology & Inflammation ranks 18 out of 59 in the Ophthalmology Category.Ocular Immunology and Inflammation is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and vision scientists. Published bimonthly, the journal provides an international medium for basic and clinical research reports on the ocular inflammatory response and its control by the immune system. The journal publishes original research papers, case reports, reviews, letters to the editor, meeting abstracts, and invited editorials.
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