{"title":"Blue plaque review series: Mabel Purefoy FitzGerald (1872–1973)","authors":"Martha Tissot van Patot","doi":"10.1113/EP092275","DOIUrl":null,"url":null,"abstract":"<p>Mabel Purefoy FitzGerald (1872–1973) was the first centenarian to receive an honorary degree from the University of Oxford. She received an honorary bachelor of the arts 68 years after being the first woman to complete the Honour School of Physiology. Her work from a solo trip through the wild and unruly mining communities high in the Colorado Rocky Mountains in 1911 revealed that to compensate for the hypoxia of high altitude, residents had lowered CO<sub>2</sub> and elevated haemoglobin. These data are some of the first to suggest a hypoxia-sensing mechanism. Until recently, her other numerous achievements and astonishing experiences struggling to become a physician at the turn of the 20th century have remained lost to history. FitzGerald's numerous accomplishments are a testament to her passion for medical science and unparalleled courage in the face of innumerable setbacks.</p>","PeriodicalId":12092,"journal":{"name":"Experimental Physiology","volume":"110 6","pages":"784-789"},"PeriodicalIF":3.0000,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1113/EP092275","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Experimental Physiology","FirstCategoryId":"3","ListUrlMain":"https://physoc.onlinelibrary.wiley.com/doi/10.1113/EP092275","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PHYSIOLOGY","Score":null,"Total":0}
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Abstract
Mabel Purefoy FitzGerald (1872–1973) was the first centenarian to receive an honorary degree from the University of Oxford. She received an honorary bachelor of the arts 68 years after being the first woman to complete the Honour School of Physiology. Her work from a solo trip through the wild and unruly mining communities high in the Colorado Rocky Mountains in 1911 revealed that to compensate for the hypoxia of high altitude, residents had lowered CO2 and elevated haemoglobin. These data are some of the first to suggest a hypoxia-sensing mechanism. Until recently, her other numerous achievements and astonishing experiences struggling to become a physician at the turn of the 20th century have remained lost to history. FitzGerald's numerous accomplishments are a testament to her passion for medical science and unparalleled courage in the face of innumerable setbacks.
期刊介绍：
Experimental Physiology publishes research papers that report novel insights into homeostatic and adaptive responses in health, as well as those that further our understanding of pathophysiological mechanisms in disease. We encourage papers that embrace the journal’s orientation of translation and integration, including studies of the adaptive responses to exercise, acute and chronic environmental stressors, growth and aging, and diseases where integrative homeostatic mechanisms play a key role in the response to and evolution of the disease process. Examples of such diseases include hypertension, heart failure, hypoxic lung disease, endocrine and neurological disorders. We are also keen to publish research that has a translational aspect or clinical application. Comparative physiology work that can be applied to aid the understanding human physiology is also encouraged.
Manuscripts that report the use of bioinformatic, genomic, molecular, proteomic and cellular techniques to provide novel insights into integrative physiological and pathophysiological mechanisms are welcomed.
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