Predictors and Consequences of Poor Health Trajectories Among US Adults Ages 50-64: A Latent Class Growth Analysis.

IF 4.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Journal of General Internal Medicine Pub Date : 2026-01-01 Epub Date: 2025-03-06 DOI:10.1007/s11606-025-09436-3
Renuka Tipirneni, Monita Karmakar, John Z Ayanian, Kara Zivin, Donovan T Maust, Kenneth M Langa
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Abstract

Background: US middle-aged adults have experienced concerning declines in health and life expectancy since 2010.

Objective: To investigate which groups of middle-aged adults are at risk of poor health trajectories, identify predictors of unhealthy aging, and assess potential consequences on health care utilization, costs, and mortality after these adults age into older adulthood.

Design: We used longitudinal survey data from the nationally representative, biennial Health and Retirement Study (HRS) to follow a representative sample of adults age 51 and older.

Participants: A total of 12,333 US community-dwelling respondents.

Main measures: We estimated health trajectories from biennial self-reported health status and limitations in activities of daily living and instrumental activities of daily living. Predictors of health trajectories included sociodemographic, clinical, and health care characteristics. Consequences of poor health trajectories after age 65 included self-reported hospitalizations, out-of-pocket medical costs, and mortality.

Key results: We identified four distinct trajectories: "Healthy Agers" (14.2%), "Less Healthy Agers" (40.7%), "Unhealthy Agers, Low Baseline" (31.0%), and "Persistently Ill" (14.1%). Predictors of the "Persistently Ill" and "Unhealthy Agers, Low Baseline" trajectories included male gender, non-Hispanic Black race, and Hispanic ethnicity. Predictors of less healthy and unhealthy aging trajectories included ≤ high school education, income ≤ 250% of federal poverty level, smoking, obesity, and chronic diseases including diabetes, whereas continuous insurance coverage in ages 50-64, compared with intermittent or no insurance, was associated with lower odds of less healthy and unhealthy aging trajectories. After age 65, less healthy and unhealthy aging trajectories were associated with greater hospitalizations, out-of-pocket costs, and mortality compared with "Healthy Agers."

Conclusion: The findings suggest that unhealthy aging trajectories may frequently be set prior to age 50. Policy interventions earlier in life, such as availability of consistent health insurance coverage in early and mid-life, may mitigate downstream poor health and health care outcomes in older adulthood.

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美国50-64岁成年人不良健康轨迹的预测因素和后果:一项潜在类别增长分析
背景:自2010年以来,美国中年人的健康状况和预期寿命都出现了令人担忧的下降。目的:调查哪些中年人有不良健康轨迹的风险,确定不健康老龄化的预测因素,并评估这些成年人进入老年后对医疗保健利用、成本和死亡率的潜在影响。设计:我们使用来自具有全国代表性的、两年一次的健康与退休研究(HRS)的纵向调查数据来跟踪51岁及以上成年人的代表性样本。参与者:共有12333名美国社区居民受访者。主要措施:我们从两年期自我报告的健康状况和日常生活活动和日常生活工具活动的限制中估计健康轨迹。健康轨迹的预测因子包括社会人口学、临床和卫生保健特征。65岁以后健康状况不佳的后果包括自我报告的住院情况、自付医疗费用和死亡率。主要结果:我们确定了四个不同的轨迹:“健康年龄”(14.2%),“不健康年龄”(40.7%),“不健康年龄,低基线”(31.0%)和“持续患病”(14.1%)。“持续患病”和“不健康年龄,低基线”轨迹的预测因子包括男性性别、非西班牙裔黑人种族和西班牙裔种族。不太健康和不健康的老龄化轨迹的预测因子包括:≤高中教育程度、收入≤联邦贫困水平的250%、吸烟、肥胖和包括糖尿病在内的慢性疾病,而与间歇性或无保险相比,50-64岁的连续保险覆盖率与不太健康和不健康老龄化轨迹的可能性较低相关。65岁以后,与“健康老年人”相比,不健康和不健康的老龄化轨迹与更高的住院率、自付费用和死亡率相关。结论:研究结果表明,不健康的衰老轨迹可能经常在50岁之前设定。生命早期的政策干预,例如在早期和中年提供一致的健康保险,可能会减轻老年期健康状况不佳和卫生保健结果。
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来源期刊
Journal of General Internal Medicine
Journal of General Internal Medicine 医学-医学:内科
CiteScore
7.70
自引率
5.30%
发文量
749
审稿时长
3-6 weeks
期刊介绍: The Journal of General Internal Medicine is the official journal of the Society of General Internal Medicine. It promotes improved patient care, research, and education in primary care, general internal medicine, and hospital medicine. Its articles focus on topics such as clinical medicine, epidemiology, prevention, health care delivery, curriculum development, and numerous other non-traditional themes, in addition to classic clinical research on problems in internal medicine.
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