{"title":"A subtype of T cells impedes tissue repair in aged spinal cord after injury.","authors":"Chengle Zhang, Kai Liu","doi":"10.1016/j.neuron.2025.02.011","DOIUrl":null,"url":null,"abstract":"<p><p>In this issue of Neuron, Kong et al.<sup>1</sup> identify targetable natural killer-like T cells that seed the intact aged human and murine spinal cords and increase further after injury. These cells impede myeloid-cell-dependent wound healing in the aged injured cord through expressing natural killer cell granule protein 7 (NKG7).</p>","PeriodicalId":19313,"journal":{"name":"Neuron","volume":"113 5","pages":"643-645"},"PeriodicalIF":14.7000,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neuron","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.neuron.2025.02.011","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
In this issue of Neuron, Kong et al.1 identify targetable natural killer-like T cells that seed the intact aged human and murine spinal cords and increase further after injury. These cells impede myeloid-cell-dependent wound healing in the aged injured cord through expressing natural killer cell granule protein 7 (NKG7).
期刊介绍：
Established as a highly influential journal in neuroscience, Neuron is widely relied upon in the field. The editors adopt interdisciplinary strategies, integrating biophysical, cellular, developmental, and molecular approaches alongside a systems approach to sensory, motor, and higher-order cognitive functions. Serving as a premier intellectual forum, Neuron holds a prominent position in the entire neuroscience community.
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