{"title":"Fighting off a gut feeling: A gut-brain-lung neuroimmune circuit.","authors":"Brian S Kim","doi":"10.1016/j.neuron.2025.01.029","DOIUrl":null,"url":null,"abstract":"<p><p>In this issue of Neuron, Chen et al. identify a postprandial neuroimmune axis by which feeding-induced stimulation of the gastrointestinal tract triggers type 2 immunity in the lung.<sup>1</sup> This study hints that there are likely distinct sensory and motor circuits coordinated by the brain across different tissues to drive neuroinflammation.</p>","PeriodicalId":19313,"journal":{"name":"Neuron","volume":"113 5","pages":"641-643"},"PeriodicalIF":14.7000,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neuron","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.neuron.2025.01.029","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
In this issue of Neuron, Chen et al. identify a postprandial neuroimmune axis by which feeding-induced stimulation of the gastrointestinal tract triggers type 2 immunity in the lung.1 This study hints that there are likely distinct sensory and motor circuits coordinated by the brain across different tissues to drive neuroinflammation.
期刊介绍:
Established as a highly influential journal in neuroscience, Neuron is widely relied upon in the field. The editors adopt interdisciplinary strategies, integrating biophysical, cellular, developmental, and molecular approaches alongside a systems approach to sensory, motor, and higher-order cognitive functions. Serving as a premier intellectual forum, Neuron holds a prominent position in the entire neuroscience community.