Fusaricate L, a new fusaric acid derivative from mangrove rhizosphere soil-derived Streptomyces angustmyceticus J-71.

IF 1.6 3区 化学 Q3 CHEMISTRY, APPLIED Natural Product Research Pub Date : 2025-03-07 DOI:10.1080/14786419.2025.2475510
Jiajia Lu, Ronghui Kuang, Jingjing Ye, Zhenyi Liang, Jing Xu
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Abstract

An undescribed fusaric acid derivative, fusaricate L (1) was isolated together with eight known compounds (2-9) from mangrove plant Rhizophora apiculata rhizosphere soil-derived Streptomyces angustmyceticus J-71. The structures of these compounds were established by extensive NMR spectroscopic data and comparison with the data of literature. Moreover, all isolated metabolites were tested for antifungal and antibacterial activities against a panel of plant and human pathogens. Compounds 4, 6, 7 and 9 showed modest antimicrobial activities towards methicillin- susceptible Staphylococcus aureus.

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红树根际土壤源链霉菌J-71的镰刀酸新衍生物fusarate L。
从红树林植物根际土壤衍生链霉菌(Streptomyces angustmyceticus J-71)中分离到一种未描述的fusaric酸衍生物fusaricate L(1)和8个已知化合物(2-9)。这些化合物的结构是通过大量的核磁共振波谱数据和与文献数据的比较确定的。此外,所有分离的代谢物都对一组植物和人类病原体进行了抗真菌和抗菌活性测试。化合物4、6、7和9对甲氧西林敏感金黄色葡萄球菌有一定的抑菌活性。
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来源期刊
Natural Product Research
Natural Product Research 化学-医药化学
CiteScore
5.10
自引率
9.10%
发文量
605
审稿时长
2.1 months
期刊介绍: The aim of Natural Product Research is to publish important contributions in the field of natural product chemistry. The journal covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds. The communications include coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussions of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, eg. fermentation chemistry, plant tissue culture investigations etc., are accepted into the journal. Natural Product Research issues will be subtitled either ""Part A - Synthesis and Structure"" or ""Part B - Bioactive Natural Products"". for details on this , see the forthcoming articles section. All manuscript submissions are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is single blind and submission is online via ScholarOne Manuscripts.
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