José L Belmonte-Vázquez, Juan L Cortes-Muñoz, Adriana Romo-Pérez, Braulio Rodríguez-Molina, Arturo Jiménez-Sánchez
{"title":"ESIPT-driven imaging: a thiazole probe for lipid droplets and plasma membranes.","authors":"José L Belmonte-Vázquez, Juan L Cortes-Muñoz, Adriana Romo-Pérez, Braulio Rodríguez-Molina, Arturo Jiménez-Sánchez","doi":"10.1039/d4cc06049k","DOIUrl":null,"url":null,"abstract":"<p><p>Fluorescence imaging allows high-resolution visualization of cellular processes. This study introduces a novel ESIPT probe with dual localization for lipid droplets and plasma membranes. Initially, the blue channel imaging reveals the probe's affinity for the plasma membrane, and then it redistributes into lipid droplets, showcasing its strong affinity for the hydrophobic lipid core.</p>","PeriodicalId":67,"journal":{"name":"Chemical Communications","volume":" ","pages":""},"PeriodicalIF":4.3000,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemical Communications","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1039/d4cc06049k","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Fluorescence imaging allows high-resolution visualization of cellular processes. This study introduces a novel ESIPT probe with dual localization for lipid droplets and plasma membranes. Initially, the blue channel imaging reveals the probe's affinity for the plasma membrane, and then it redistributes into lipid droplets, showcasing its strong affinity for the hydrophobic lipid core.
期刊介绍:
ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.