Diazepam, Meperidine, and Hydroxyzine as a Moderate Sedation Regimen in Pediatric Dentistry: A Retrospective Study.

IF 1.9 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE International journal of paediatric dentistry Pub Date : 2025-09-01 Epub Date: 2025-03-09 DOI:10.1111/ipd.13305

Taibah Albaker, Caroline Carrico, Daniel Hawkins, Tiffany Williams

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引用次数: 0

Abstract

Background: Moderate sedation is a behavior guidance technique in pediatric dentistry, and evaluating existing regimens can improve sedation outcomes and safety.

Aim: To determine if behavior at consult and sedation medication dosages is associated with sedation success and the patient's behavior using diazepam, meperidine, and hydroxyzine (DMH) regimen.

Design: A retrospective chart review of 324 patients who underwent 404 oral moderate sedations with (DMH) from April 2017 to June 2022. Sedations were graded as Successful or Unsuccessful and Positive (Frankl F3 or F4) or Negative (Frankl F1 or F2) behavior. Primary variables included Frankl behavior at consult and medication dosages. Logistic regression models were used to determine if these factors were associated with sedation success and behavior while adjusting for other patient and sedation characteristics.

Results: DMH yielded mostly successful sedations (89%) and Positive Behavior (Frankl F3 or F4) (72%). Lower Frankl scores at consult (OR: 2.3, p = 0.0140) were associated with increased odds of sedation failure. Increased age (OR: 0.8, p = 0.0047) was associated with decreased odds of failure. Meperidine dose demonstrated a significant association with improved sedation while controlling for age and behavior (p < 0.0001).

Conclusion: The (DMH) is an effective moderate sedation regimen. Patient selection is a significant factor in sedation success.

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地西泮、哌啶和羟嗪作为小儿牙科的中度镇静方案：一项回顾性研究。

背景：适度镇静是儿科牙科的一种行为指导技术，对现有方案进行评估可以改善镇静效果和安全性。目的：确定会诊时的行为和镇静药物剂量是否与镇静成功和患者使用地西泮、哌嗪和羟嗪（DMH）方案的行为有关。设计：对2017年4月至2022年6月期间接受404例口服（DMH）中度镇静治疗的324例患者进行回顾性图表回顾。镇静分为成功或不成功、阳性（Frankl F3或F4）或阴性（Frankl F1或F2）行为。主要变量包括咨询时的Frankl行为和用药剂量。使用逻辑回归模型来确定这些因素是否与镇静成功和行为相关，同时调整其他患者和镇静特征。结果：DMH产生大部分成功镇静（89%）和积极行为（Frankl F3或F4）（72%）。咨询时较低的Frankl评分（OR: 2.3, p = 0.0140）与镇静失败的几率增加相关。年龄增加（OR: 0.8, p = 0.0047）与失败几率降低相关。在控制年龄和行为的情况下，哌哌啶剂量与镇静效果显著相关(p结论：（DMH）是一种有效的中度镇静方案。患者选择是镇静成功的重要因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International journal of paediatric dentistry 医学-小儿科

CiteScore

5.50

自引率

2.60%

发文量

审稿时长

6-12 weeks

期刊介绍： The International Journal of Paediatric Dentistry was formed in 1991 by the merger of the Journals of the International Association of Paediatric Dentistry and the British Society of Paediatric Dentistry and is published bi-monthly. It has true international scope and aims to promote the highest standard of education, practice and research in paediatric dentistry world-wide. International Journal of Paediatric Dentistry publishes papers on all aspects of paediatric dentistry including: growth and development, behaviour management, diagnosis, prevention, restorative treatment and issue relating to medically compromised children or those with disabilities. This peer-reviewed journal features scientific articles, reviews, case reports, clinical techniques, short communications and abstracts of current paediatric dental research. Analytical studies with a scientific novelty value are preferred to descriptive studies. Case reports illustrating unusual conditions and clinically relevant observations are acceptable but must be of sufficiently high quality to be considered for publication; particularly the illustrative material must be of the highest quality.