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Consensus-Based Recommendations on Pulp Therapies in Primary and Permanent Teeth: IAPD Porto Forum. 基于共识的乳牙和恒牙牙髓治疗建议:IAPD波尔图论坛。
IF 1.9 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-02-02 DOI: 10.1111/ipd.70068
Vineet Dhar, Ikhlas El-Karim, James A Coll, Ashraf F Fouad, Anne C O'Connell, Saeed Asgary, Lars Bjørndal, Zafer C Cehreli, Yasmi O Crystal, Manikandan Ekambaram, Brian D Hodgson, Nicola P Innes, Jonas Almeida Rodrigues, Nessrin A Taha, Nitesh Tewari, Tugba Turk

Background: Recent understanding of pulp biology has shifted treatment paradigms toward preservation-based approaches. Traditional diagnostic terminology and treatment protocols require updating to align with current evidence supporting the pulp's healing capacity.

Aim: Sixteen international specialists in pediatric dentistry and endodontics convened at the 3rd IAPD Summit in Porto, Portugal (November 2024) to develop consensus-based recommendations on pulp therapies in primary and permanent teeth.

Methods: Following a structured three-phase approach, experts conducted systematic literature reviews and participated in Delphi surveys using a 7-point Likert scale. Recommendations achieving > 70% consensus were categorized as strong (based on RCTs/systematic reviews), conditional (observational studies), or consensus-based statements (expert opinion).

Results: Thirty-eight evidence-based recommendations were developed across four key areas: pulp inflammation and diagnosis, caries excavation, management of pulpitis in primary and permanent teeth, and traumatic dental injuries. Key findings emphasized selective caries removal over complete excavation, calcium silicate cements as preferred materials for vital pulp therapy, and conservative approaches for managing irreversible pulpitis. Decision trees were created to support clinical implementation.

Conclusions: These consensus recommendations provide evidence-based guidance for managing pulpal diseases using minimally invasive, biologically driven tiered approaches that prioritize pulp preservation in both primary and permanent teeth.

背景:最近对牙髓生物学的理解已经将治疗范式转向了基于保存的方法。传统的诊断术语和治疗方案需要更新,以符合当前支持牙髓愈合能力的证据。目的:16位国际儿科牙科和牙髓学专家于2024年11月在葡萄牙波尔图举行的第三届IAPD峰会上齐聚一堂,就乳牙和恒牙的牙髓治疗提出基于共识的建议。方法:按照结构化的三阶段方法,专家们进行了系统的文献综述,并使用7分李克特量表参与了德尔菲调查。达到70%共识的建议被分类为强烈(基于随机对照试验/系统评价)、有条件(观察性研究)或基于共识的陈述(专家意见)。结果:在四个关键领域提出了38项基于证据的建议:牙髓炎症和诊断,龋齿挖掘,乳牙和恒牙牙髓炎的管理,以及创伤性牙损伤。主要研究结果强调了选择性龋齿清除而不是完全挖掘,硅酸钙胶合剂是重要牙髓治疗的首选材料,以及治疗不可逆牙髓炎的保守方法。决策树的创建是为了支持临床实施。结论:这些一致的建议为采用微创、生物驱动的分层方法治疗牙髓疾病提供了循证指导,优先考虑乳牙和恒牙的牙髓保护。
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引用次数: 0
Dental Caries Prevalence Among Dubai and Northern Emirates Public Schoolchildren: An Epidemiological Retrospective Study (2015-2019). 迪拜和阿联酋北部公立学校学童龋齿患病率:流行病学回顾性研究(2015-2019)
IF 1.9 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-29 DOI: 10.1111/ipd.70074
Khawla Humaid Belhoul Alfalasi, Tom Loney, Momen Atieh, Christopher Cardwell, Haifa Hannawi, Maimouneh Qazi, Gerry McKenna

Background: Oral health is a key public health priority in the United Arab Emirates (UAE), yet the effectiveness of the existing programmes is unclear due to limited standardised data.

Aim: To estimate schoolchildren caries prevalence across UAE over five academic years (2015-2019) and assess the associated factors.

Methods: Secondary data analysis from a national oral health screening, by the Ministry of Health and Prevention in government schools across six emirates. Students in Grade 1 (6-8 years old), Grade 7 (12-14 years old) and Grade 10 (15-17 years old) were screened between 2015 and 2019.

Results: A total of 131 451 students were screened. Overall caries prevalence was high at 60.9%, declining from 65.1% in 2015 to 49.19% in 2019 (OR = 0.51, 95% CI: 0.49-0.53, p < 0.001, compared to 2015). Prevalence was the lowest in Dubai (55.2%), and the highest in Fujairah (75.0%, OR = 2.57, 95% CI: 2.46-2.67, p < 0.001, compared to Dubai). Grade 1 students had the highest prevalence (70.5%), while both Grade 7 (55.1%; OR = 0.51; 95% CI: 0.49-0.52; p < 0.001, compared to Grade 1) and Grade 10 (57.9%; OR = 0.58; 95% CI: 0.56-0.59; p < 0.001, compared to Grade 1) were the lowest.

Conclusion: Dental caries remains highly prevalent among UAE schoolchildren, particularly in Fujairah and younger age groups. Standardised, integrated oral health policy and planning are instantly needed across the Emirates.

背景:口腔健康是阿拉伯联合酋长国(UAE)的一项关键公共卫生重点,但由于标准化数据有限,现有规划的有效性尚不清楚。目的:估计阿联酋五个学年(2015-2019)学童龋齿患病率,并评估相关因素。方法:由卫生和预防部在六个酋长国的公立学校进行的全国口腔健康筛查的二次数据分析。在2015年至2019年期间,对一年级(6-8岁)、七年级(12-14岁)和十年级(15-17岁)的学生进行了筛选。结果:共筛查131451名学生。总体龋齿患病率为60.9%,从2015年的65.1%下降到2019年的49.19% (OR = 0.51, 95% CI: 0.49-0.53, p)。结论:龋齿在阿联酋学童中仍然非常普遍,特别是在富查伊拉和更年轻的年龄组。阿联酋各地迫切需要标准化、综合的口腔卫生政策和规划。
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引用次数: 0
Looking Ahead: The Next Chapter for IJPD. 展望未来:IJPD的下一个篇章。
IF 1.9 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-26 DOI: 10.1111/ipd.70076
Nicola Innes
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引用次数: 0
Pulp Therapies Rooted in Evidence: IAPD Porto Declaration. 基于证据的牙髓治疗:IAPD波尔图宣言。
IF 1.9 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-14 DOI: 10.1111/ipd.70073
Vineet Dhar, Ikhlas El-Karim, James A Coll, Ashraf F Fouad, Anne C O'Connell, Saeed Asgary, Lars Bjørndal, Zafer C Cehreli, Yasmi O Crystal, Manikandan Ekambaram, Brian D Hodgson, Nicola P Innes, Jonas Almeida Rodrigues, Nessrin A Taha, Nitesh Tewari, Tugba Turk
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引用次数: 0
The Use of Puppetry-Based Approaches in Dental and Oral Health Promotion for Children: A Scoping Review of Interventions. 使用基于木偶戏的方法促进儿童的牙齿和口腔健康:干预措施的范围审查。
IF 1.9 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-11 DOI: 10.1111/ipd.70072
Lama Ahmed Alosail, Maram Ali Alwadi, Deema Alroweilly, Khalid Saleh Alshayea, Saud Hamad Alzuhair, Basil H Aboul-Enein

Background: Puppetry is a well-established three-dimensional art form of media that has been commonly utilized to tell stories and communicate messages. Its application in educational entertainment has become widespread and gained recognition.

Aim: This scoping review aimed to explore puppetry-based approaches in promoting dental and oral health for children.

Methods: A comprehensive search of eight databases was conducted using PRISMA-ScR guidelines, focusing on studies published up to August 2024.

Results: Ten studies were included in the review. A game-centered educational approach significantly enhanced children's dental knowledge and skills. Human models with mirror feedback were most effective, while giant tooth-brushing models and animal puppets had the lowest imitation rates. Puppet theater improved urban preschoolers' oral health but had no effect on rural children. Hand puppets, pop-up books, and animated videos significantly enhanced toothbrushing skills. Storytelling with hand puppets improved knowledge and attitude more than role-playing. Puppet shows and animated videos yielded notable posttest improvements in oral health knowledge and skills.

Conclusion: Puppetry-based education appears to be an effective strategy for improving oral health knowledge, attitudes, and behaviors among children, particularly in school and clinical settings.

背景:木偶戏是一种成熟的三维艺术形式,通常用于讲故事和传达信息。它在教育娱乐中的应用已经得到了广泛的认可。目的:本综述旨在探讨以木偶戏为基础的促进儿童牙齿和口腔健康的方法。方法:采用PRISMA-ScR指南对8个数据库进行全面检索,重点检索截至2024年8月发表的研究。结果:纳入10项研究。以游戏为中心的教育方法显著提高了儿童的牙科知识和技能。具有镜像反馈的人体模型最有效,而巨大的刷牙模型和动物木偶的模仿率最低。木偶剧改善了城市学龄前儿童的口腔健康,但对农村儿童没有影响。手偶、立体书和动画视频显著提高了刷牙技巧。用手木偶讲故事比角色扮演更能提高知识和态度。木偶戏和动画视频在口腔健康知识和技能的测试后显著提高。结论:以木偶为基础的教育似乎是改善儿童口腔健康知识、态度和行为的有效策略,特别是在学校和临床环境中。
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引用次数: 0
Closing Editorial 关闭编辑。
IF 1.9 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-08 DOI: 10.1111/ipd.70067
Donald L. Chi
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引用次数: 0
Evaluation of Salivary IL-2, IL-5, and IL-17 Levels in Paediatric Patients Treated With Stainless Steel Crowns. 不锈钢牙冠治疗儿童患者唾液IL-2、IL-5和IL-17水平的评价
IF 1.9 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-30 DOI: 10.1111/ipd.70071
Burcin Avci, Alaettin Koç, Sema Kaya

Background: Salivary cytokine assessment provides a non-invasive method to evaluate the biocompatibility of metal-based restorative materials in paediatric dentistry. Changes in IL-17 may indicate early immunological responses to stainless steel crowns (SSCs).

Aim: To investigate salivary IL-2, IL-5, and IL-17 levels in children treated with SSCs and explore their potential immunological implications.

Design: Ten paediatric patients aged 3-9 years were included in this prospective study. Unstimulated whole saliva was collected before treatment and 7 days after SSC placement. Cytokine expression was measured using RT-qPCR. Statistical analyses included one-way ANOVA for cytokine expression and the Wilcoxon signed-rank test for salivary nickel and chromium levels, with p < 0.05 considered significant.

Results: Baseline IL-2, IL-5, and IL-17 levels were low and comparable. 7 days after SSC placement, all cytokines increased. IL-17 and IL-5 showed significant upregulation, whereas IL-2 demonstrated only a minor, non-significant change. Salivary nickel and chromium concentrations increased mildly but remained well below established safety thresholds.

Conclusion: Stainless steel crowns (SSC) placement was associated with increased IL-5 and IL-17 expression, suggesting a localised, subclinical immune response potentially linked to low-level metal-ion exposure. These findings support the use of salivary cytokines as early biomarkers for assessing the biocompatibility and immunological safety of SSCs in paediatric patients.

Trial registration: ClinicalTrials.gov identifier: (NCT06439095).

背景:唾液细胞因子评估为评估儿童牙科金属基修复材料的生物相容性提供了一种无创方法。IL-17的变化可能预示着对不锈钢冠(ssc)的早期免疫反应。目的:研究SSCs治疗儿童唾液IL-2、IL-5和IL-17的水平,并探讨其潜在的免疫学意义。设计:10例3-9岁的儿童患者被纳入这项前瞻性研究。在治疗前和SSC放置后7天采集未受刺激的全唾液。采用RT-qPCR检测细胞因子表达。统计分析包括细胞因子表达的单因素方差分析和唾液中镍和铬水平的Wilcoxon标记秩检验,结果:基线IL-2、IL-5和IL-17水平较低且具有可比性。SSC放置7天后,所有细胞因子均升高。IL-17和IL-5表现出显著的上调,而IL-2仅表现出轻微的、不显著的变化。唾液中镍和铬的浓度略有增加,但仍远低于既定的安全阈值。结论:不锈钢冠(SSC)放置与IL-5和IL-17表达增加相关,提示局部亚临床免疫反应可能与低水平金属离子暴露有关。这些发现支持使用唾液细胞因子作为早期生物标志物来评估SSCs在儿科患者中的生物相容性和免疫安全性。试验注册:ClinicalTrials.gov识别码:(NCT06439095)。
{"title":"Evaluation of Salivary IL-2, IL-5, and IL-17 Levels in Paediatric Patients Treated With Stainless Steel Crowns.","authors":"Burcin Avci, Alaettin Koç, Sema Kaya","doi":"10.1111/ipd.70071","DOIUrl":"https://doi.org/10.1111/ipd.70071","url":null,"abstract":"<p><strong>Background: </strong>Salivary cytokine assessment provides a non-invasive method to evaluate the biocompatibility of metal-based restorative materials in paediatric dentistry. Changes in IL-17 may indicate early immunological responses to stainless steel crowns (SSCs).</p><p><strong>Aim: </strong>To investigate salivary IL-2, IL-5, and IL-17 levels in children treated with SSCs and explore their potential immunological implications.</p><p><strong>Design: </strong>Ten paediatric patients aged 3-9 years were included in this prospective study. Unstimulated whole saliva was collected before treatment and 7 days after SSC placement. Cytokine expression was measured using RT-qPCR. Statistical analyses included one-way ANOVA for cytokine expression and the Wilcoxon signed-rank test for salivary nickel and chromium levels, with p < 0.05 considered significant.</p><p><strong>Results: </strong>Baseline IL-2, IL-5, and IL-17 levels were low and comparable. 7 days after SSC placement, all cytokines increased. IL-17 and IL-5 showed significant upregulation, whereas IL-2 demonstrated only a minor, non-significant change. Salivary nickel and chromium concentrations increased mildly but remained well below established safety thresholds.</p><p><strong>Conclusion: </strong>Stainless steel crowns (SSC) placement was associated with increased IL-5 and IL-17 expression, suggesting a localised, subclinical immune response potentially linked to low-level metal-ion exposure. These findings support the use of salivary cytokines as early biomarkers for assessing the biocompatibility and immunological safety of SSCs in paediatric patients.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov identifier: (NCT06439095).</p>","PeriodicalId":14268,"journal":{"name":"International journal of paediatric dentistry","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145862780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transillumination-Aided Infiltration of MIH-Affected Molars: Evaluation of the Clinical Workflow. 照度辅助下mih影响磨牙浸润:临床工作流程的评价。
IF 1.9 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-29 DOI: 10.1111/ipd.70064
Omar Marouane, Mariem Nefzaoui, David John Manton, Marcus Cebula, Falk Schwendicke, Susanne Effenberger

Background: Enamel affected by molar incisor hypomineralisation (MIH) exhibits reduced mechanical properties due to its disorganised prismatic structure, lower mineral density and higher protein content. These alterations increase porosity and susceptibility to posteruptive enamel breakdown. Minimally invasive treatments, such as resin infiltration, have been proposed to reinforce enamel integrity. Recent advances suggest that transillumination can guide infiltration more accurately, allowing better visualisation of lesion extent and potentially improving treatment outcomes.

Aim: This case series evaluated the clinical suitability of transillumination-aided resin infiltration, specifically the utility of using transillumination to support resin infiltration treatment, for MIH-affected molars.

Design: Five MIH-affected first permanent molars from five paediatric patients, diagnosed according to EAPD criteria for MIH, were included. One molar presented with two distinct lesions, leading to the inclusion of six lesions in total. Transillumination was used to assess the lesion appearance, to assist with selective surface removal and to monitor the resin infiltration process to assess when it was completed, that is, when the lesion either fully disappeared visually or no change was visible anymore under transmitted light.

Results: Transillumination was employed successfully to assist with resin infiltration treatment and to assess the treatment outcome. Four lesions showed partial and two complete infiltrations visually, indicating putatively that the porous lesion structure is strengthened. No complications were reported during treatment.

Conclusions: Transillumination was successfully utilised to support resin infiltration in MIH-affected molars and to visualise the quality of infiltration, serving as a potential surrogate outcome measure. Future research should explore long-term clinical outcomes and the impact on patients' quality of life.

背景:受磨牙低矿化(MIH)影响的牙釉质由于其无序的棱柱状结构、较低的矿物质密度和较高的蛋白质含量而表现出力学性能降低。这些改变增加了孔隙度和对后牙釉质破裂的易感性。微创治疗,如树脂浸润,已被提出加强牙釉质完整性。最近的进展表明,透照可以更准确地指导浸润,从而更好地显示病变范围,并可能改善治疗结果。目的:本病例系列评估透照辅助树脂浸润治疗mih影响磨牙的临床适用性,特别是使用透照辅助树脂浸润治疗的实用性。设计:根据EAPD诊断MIH的标准,包括5名儿童患者的5颗MIH影响的第一恒磨牙。一个磨牙呈现出两个不同的病变,导致总共包括六个病变。透射光用于评估病变外观,协助选择性表面去除,并监测树脂浸润过程以评估其完成时间,即病变在透射光下完全消失或不再可见变化。结果:透照成功地辅助了树脂浸润治疗,并评估了治疗效果。4个病灶可见部分浸润,2个完全浸润,推测病变多孔性结构加强。治疗期间无并发症发生。结论:透射照明成功地支持树脂在mih影响磨牙的浸润,并显示浸润质量,作为潜在的替代结果测量。未来的研究应探索长期临床结果和对患者生活质量的影响。
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引用次数: 0
Dental Caries as a Potential Risk Factor for Asthma: Evidence From Mendelian Randomization Analysis. 龋齿是哮喘的潜在危险因素:来自孟德尔随机化分析的证据。
IF 1.9 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-28 DOI: 10.1111/ipd.70070
Chenchen Wang, Jiaming Liu, Ping Luo, Wanting Wan, Jifang Hui, Wenhui Liang, Jingjing Liu, Hu Qiao

Background: Dental caries is a widespread oral disease linked to systemic health. Asthma, a chronic airway condition, impacts quality of life and may influence oral health. While evidence on the association between asthma and caries is inconclusive, some studies suggest asthma increases caries risk. This study applies Mendelian randomization (MR) to investigate their potential causal relationship.

Methods: A bidirectional MR analysis was conducted using publicly available genome-wide association studies (GWAS) data. Suitable instrumental variables (IVs) were chosen in accordance with three key MR analysis assumptions. The primary method employed was the inverse-variance weighted (IVW) method, with supplementary methods including MR-Egger regression, Weighted Median, Simple Mode, Weighted Mode, and the MR pleiotropy residual sum and outlier techniques.

Results: MR analysis showed a significant positive association between dental caries and asthma (IVW OR > 1, p < 0.05). No causal effect of asthma on dental caries was detected (p > 0.05). Sensitivity analyses confirmed no heterogeneity or pleiotropy, supporting the robustness of these findings.

Conclusions: This study suggests that dental caries may contribute to asthma development, while asthma does not directly influence dental caries. Maintaining good oral health could help reduce asthma risk, highlighting the need for integrated oral and respiratory health strategies.

背景:龋齿是一种广泛存在的与全身健康相关的口腔疾病。哮喘是一种慢性气道疾病,会影响生活质量,并可能影响口腔健康。虽然哮喘和龋齿之间的关系尚无定论,但一些研究表明,哮喘会增加龋齿的风险。本研究应用孟德尔随机化(MR)来研究它们之间潜在的因果关系。方法:利用公开的全基因组关联研究(GWAS)数据进行双向磁共振分析。根据三个关键的MR分析假设选择合适的工具变量。采用的主要方法是反方差加权(IVW)方法,辅助方法包括MR- egger回归、加权中位数、简单模式、加权模式以及MR多效性残差和异常值技术。结果:MR分析显示龋病与哮喘呈显著正相关(IVW OR >1, p 0.05)。敏感性分析证实无异质性或多效性,支持这些发现的稳健性。结论:本研究提示龋齿可能促进哮喘的发展,而哮喘并不直接影响龋齿。保持良好的口腔健康有助于降低哮喘风险,强调需要采取综合口腔和呼吸健康战略。
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引用次数: 0
Association Between Oral Diadochokinesis, Grade and Sex in Japanese Elementary School Children: A Cross-Sectional Analysis From the Kuroishi Oral Health Study. 日本小学生口腔发育、年级和性别之间的关系:来自Kuroishi口腔健康研究的横断面分析。
IF 1.9 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-28 DOI: 10.1111/ipd.70069
Kaichi Hayashi, Keishi Sato, Satoru Morishita, Itoyo Tokuda, Keiji Wada, Shintaro Yokoyama, Tsukasa Tanaka, Kaori Sawada, Kei Kurita, Toyoaki Ashida, Koichi Murashita, Tatsuya Mikami, Shigeyuki Nakaji, Wataru Kobayashi

Background: Tongue-lip motor function is essential for speech and swallowing. However, research on oral diadochokinesis (ODK), an indicator of this function, remains limited among Japanese children.

Aim: To provide foundational ODK data in Japanese children and examine its associations with grade, sex and dental and anthropometric variables.

Design: Data from the 2022-2023 Kuroishi Oral Health Study were analysed for 464 third- to sixth-grade students. ODK (/pa/, /ta/, /ka/), grade, sex, total number of teeth, decayed, missing and filled permanent teeth (DMFT) index, and body mass index (BMI) were examined using analysis of variance, t-tests, and multiple regression.

Results: Mean ODK values increased with grade, with sixth-graders showing significantly higher values than third-, fourth- or fifth-graders. Across all syllables, girls showed significantly higher values than boys in fourth or fifth grades, with no significant differences in third or sixth grades. No significant associations were found between ODK and the total number of teeth, DMFT index or BMI.

Conclusion: This study provides foundational ODK data in Japanese children, highlighting grade- and sex-related variations. These findings enhance the understanding of tongue-lip motor function development and may serve as a reference for future research and clinical assessments.

背景:舌唇运动功能对语言和吞咽是必不可少的。然而,关于口腔内分泌功能(ODK)的研究,这一功能的指标,在日本儿童中仍然有限。目的:提供日本儿童的基本ODK数据,并研究其与年级、性别、牙齿和人体测量变量的关系。设计:分析了来自2022-2023年Kuroishi口腔健康研究的464名三至六年级学生的数据。采用方差分析、t检验、多元回归等方法,对ODK (/pa/、/ta/、/ka/)、牙级、性别、牙总数、恒牙蛀牙、缺牙和补牙(DMFT)指数、体重指数(BMI)进行分析。结果:平均ODK值随着年级的增加而增加,六年级的ODK值明显高于三年级、四年级和五年级。在所有音节中,女孩在四年级和五年级表现出明显高于男孩的价值,在三年级和六年级没有显著差异。ODK与牙齿总数、DMFT指数或BMI之间无显著相关性。结论:本研究提供了日本儿童ODK的基础数据,突出了年级和性别相关的差异。这些发现增强了对舌唇运动功能发育的认识,可为今后的研究和临床评估提供参考。
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引用次数: 0
期刊
International journal of paediatric dentistry
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