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Pulp Therapies Rooted in Evidence: IAPD Porto Declaration. 基于证据的牙髓治疗:IAPD波尔图宣言。
IF 1.9 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-14 DOI: 10.1111/ipd.70073
Vineet Dhar, Ikhlas El-Karim, James A Coll, Ashraf F Fouad, Anne C O'Connell, Saeed Asgary, Lars Bjørndal, Zafer C Cehreli, Yasmi O Crystal, Manikandan Ekambaram, Brian D Hodgson, Nicola P Innes, Jonas Almedia Rodrigues, Nessrin A Taha, Nitesh Tewari, Tugba Turk
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引用次数: 0
The Use of Puppetry-Based Approaches in Dental and Oral Health Promotion for Children: A Scoping Review of Interventions. 使用基于木偶戏的方法促进儿童的牙齿和口腔健康:干预措施的范围审查。
IF 1.9 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-11 DOI: 10.1111/ipd.70072
Lama Ahmed Alosail, Maram Ali Alwadi, Deema Alroweilly, Khalid Saleh Alshayea, Saud Hamad Alzuhair, Basil H Aboul-Enein

Background: Puppetry is a well-established three-dimensional art form of media that has been commonly utilized to tell stories and communicate messages. Its application in educational entertainment has become widespread and gained recognition.

Aim: This scoping review aimed to explore puppetry-based approaches in promoting dental and oral health for children.

Methods: A comprehensive search of eight databases was conducted using PRISMA-ScR guidelines, focusing on studies published up to August 2024.

Results: Ten studies were included in the review. A game-centered educational approach significantly enhanced children's dental knowledge and skills. Human models with mirror feedback were most effective, while giant tooth-brushing models and animal puppets had the lowest imitation rates. Puppet theater improved urban preschoolers' oral health but had no effect on rural children. Hand puppets, pop-up books, and animated videos significantly enhanced toothbrushing skills. Storytelling with hand puppets improved knowledge and attitude more than role-playing. Puppet shows and animated videos yielded notable posttest improvements in oral health knowledge and skills.

Conclusion: Puppetry-based education appears to be an effective strategy for improving oral health knowledge, attitudes, and behaviors among children, particularly in school and clinical settings.

背景:木偶戏是一种成熟的三维艺术形式,通常用于讲故事和传达信息。它在教育娱乐中的应用已经得到了广泛的认可。目的:本综述旨在探讨以木偶戏为基础的促进儿童牙齿和口腔健康的方法。方法:采用PRISMA-ScR指南对8个数据库进行全面检索,重点检索截至2024年8月发表的研究。结果:纳入10项研究。以游戏为中心的教育方法显著提高了儿童的牙科知识和技能。具有镜像反馈的人体模型最有效,而巨大的刷牙模型和动物木偶的模仿率最低。木偶剧改善了城市学龄前儿童的口腔健康,但对农村儿童没有影响。手偶、立体书和动画视频显著提高了刷牙技巧。用手木偶讲故事比角色扮演更能提高知识和态度。木偶戏和动画视频在口腔健康知识和技能的测试后显著提高。结论:以木偶为基础的教育似乎是改善儿童口腔健康知识、态度和行为的有效策略,特别是在学校和临床环境中。
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引用次数: 0
Closing Editorial 关闭编辑。
IF 1.9 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-08 DOI: 10.1111/ipd.70067
Donald L. Chi
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引用次数: 0
Evaluation of Salivary IL-2, IL-5, and IL-17 Levels in Paediatric Patients Treated With Stainless Steel Crowns. 不锈钢牙冠治疗儿童患者唾液IL-2、IL-5和IL-17水平的评价
IF 1.9 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-30 DOI: 10.1111/ipd.70071
Burcin Avci, Alaettin Koç, Sema Kaya

Background: Salivary cytokine assessment provides a non-invasive method to evaluate the biocompatibility of metal-based restorative materials in paediatric dentistry. Changes in IL-17 may indicate early immunological responses to stainless steel crowns (SSCs).

Aim: To investigate salivary IL-2, IL-5, and IL-17 levels in children treated with SSCs and explore their potential immunological implications.

Design: Ten paediatric patients aged 3-9 years were included in this prospective study. Unstimulated whole saliva was collected before treatment and 7 days after SSC placement. Cytokine expression was measured using RT-qPCR. Statistical analyses included one-way ANOVA for cytokine expression and the Wilcoxon signed-rank test for salivary nickel and chromium levels, with p < 0.05 considered significant.

Results: Baseline IL-2, IL-5, and IL-17 levels were low and comparable. 7 days after SSC placement, all cytokines increased. IL-17 and IL-5 showed significant upregulation, whereas IL-2 demonstrated only a minor, non-significant change. Salivary nickel and chromium concentrations increased mildly but remained well below established safety thresholds.

Conclusion: Stainless steel crowns (SSC) placement was associated with increased IL-5 and IL-17 expression, suggesting a localised, subclinical immune response potentially linked to low-level metal-ion exposure. These findings support the use of salivary cytokines as early biomarkers for assessing the biocompatibility and immunological safety of SSCs in paediatric patients.

Trial registration: ClinicalTrials.gov identifier: (NCT06439095).

背景:唾液细胞因子评估为评估儿童牙科金属基修复材料的生物相容性提供了一种无创方法。IL-17的变化可能预示着对不锈钢冠(ssc)的早期免疫反应。目的:研究SSCs治疗儿童唾液IL-2、IL-5和IL-17的水平,并探讨其潜在的免疫学意义。设计:10例3-9岁的儿童患者被纳入这项前瞻性研究。在治疗前和SSC放置后7天采集未受刺激的全唾液。采用RT-qPCR检测细胞因子表达。统计分析包括细胞因子表达的单因素方差分析和唾液中镍和铬水平的Wilcoxon标记秩检验,结果:基线IL-2、IL-5和IL-17水平较低且具有可比性。SSC放置7天后,所有细胞因子均升高。IL-17和IL-5表现出显著的上调,而IL-2仅表现出轻微的、不显著的变化。唾液中镍和铬的浓度略有增加,但仍远低于既定的安全阈值。结论:不锈钢冠(SSC)放置与IL-5和IL-17表达增加相关,提示局部亚临床免疫反应可能与低水平金属离子暴露有关。这些发现支持使用唾液细胞因子作为早期生物标志物来评估SSCs在儿科患者中的生物相容性和免疫安全性。试验注册:ClinicalTrials.gov识别码:(NCT06439095)。
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引用次数: 0
Transillumination-Aided Infiltration of MIH-Affected Molars: Evaluation of the Clinical Workflow. 照度辅助下mih影响磨牙浸润:临床工作流程的评价。
IF 1.9 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-29 DOI: 10.1111/ipd.70064
Omar Marouane, Mariem Nefzaoui, David John Manton, Marcus Cebula, Falk Schwendicke, Susanne Effenberger

Background: Enamel affected by molar incisor hypomineralisation (MIH) exhibits reduced mechanical properties due to its disorganised prismatic structure, lower mineral density and higher protein content. These alterations increase porosity and susceptibility to posteruptive enamel breakdown. Minimally invasive treatments, such as resin infiltration, have been proposed to reinforce enamel integrity. Recent advances suggest that transillumination can guide infiltration more accurately, allowing better visualisation of lesion extent and potentially improving treatment outcomes.

Aim: This case series evaluated the clinical suitability of transillumination-aided resin infiltration, specifically the utility of using transillumination to support resin infiltration treatment, for MIH-affected molars.

Design: Five MIH-affected first permanent molars from five paediatric patients, diagnosed according to EAPD criteria for MIH, were included. One molar presented with two distinct lesions, leading to the inclusion of six lesions in total. Transillumination was used to assess the lesion appearance, to assist with selective surface removal and to monitor the resin infiltration process to assess when it was completed, that is, when the lesion either fully disappeared visually or no change was visible anymore under transmitted light.

Results: Transillumination was employed successfully to assist with resin infiltration treatment and to assess the treatment outcome. Four lesions showed partial and two complete infiltrations visually, indicating putatively that the porous lesion structure is strengthened. No complications were reported during treatment.

Conclusions: Transillumination was successfully utilised to support resin infiltration in MIH-affected molars and to visualise the quality of infiltration, serving as a potential surrogate outcome measure. Future research should explore long-term clinical outcomes and the impact on patients' quality of life.

背景:受磨牙低矿化(MIH)影响的牙釉质由于其无序的棱柱状结构、较低的矿物质密度和较高的蛋白质含量而表现出力学性能降低。这些改变增加了孔隙度和对后牙釉质破裂的易感性。微创治疗,如树脂浸润,已被提出加强牙釉质完整性。最近的进展表明,透照可以更准确地指导浸润,从而更好地显示病变范围,并可能改善治疗结果。目的:本病例系列评估透照辅助树脂浸润治疗mih影响磨牙的临床适用性,特别是使用透照辅助树脂浸润治疗的实用性。设计:根据EAPD诊断MIH的标准,包括5名儿童患者的5颗MIH影响的第一恒磨牙。一个磨牙呈现出两个不同的病变,导致总共包括六个病变。透射光用于评估病变外观,协助选择性表面去除,并监测树脂浸润过程以评估其完成时间,即病变在透射光下完全消失或不再可见变化。结果:透照成功地辅助了树脂浸润治疗,并评估了治疗效果。4个病灶可见部分浸润,2个完全浸润,推测病变多孔性结构加强。治疗期间无并发症发生。结论:透射照明成功地支持树脂在mih影响磨牙的浸润,并显示浸润质量,作为潜在的替代结果测量。未来的研究应探索长期临床结果和对患者生活质量的影响。
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引用次数: 0
Dental Caries as a Potential Risk Factor for Asthma: Evidence From Mendelian Randomization Analysis. 龋齿是哮喘的潜在危险因素:来自孟德尔随机化分析的证据。
IF 1.9 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-28 DOI: 10.1111/ipd.70070
Chenchen Wang, Jiaming Liu, Ping Luo, Wanting Wan, Jifang Hui, Wenhui Liang, Jingjing Liu, Hu Qiao

Background: Dental caries is a widespread oral disease linked to systemic health. Asthma, a chronic airway condition, impacts quality of life and may influence oral health. While evidence on the association between asthma and caries is inconclusive, some studies suggest asthma increases caries risk. This study applies Mendelian randomization (MR) to investigate their potential causal relationship.

Methods: A bidirectional MR analysis was conducted using publicly available genome-wide association studies (GWAS) data. Suitable instrumental variables (IVs) were chosen in accordance with three key MR analysis assumptions. The primary method employed was the inverse-variance weighted (IVW) method, with supplementary methods including MR-Egger regression, Weighted Median, Simple Mode, Weighted Mode, and the MR pleiotropy residual sum and outlier techniques.

Results: MR analysis showed a significant positive association between dental caries and asthma (IVW OR > 1, p < 0.05). No causal effect of asthma on dental caries was detected (p > 0.05). Sensitivity analyses confirmed no heterogeneity or pleiotropy, supporting the robustness of these findings.

Conclusions: This study suggests that dental caries may contribute to asthma development, while asthma does not directly influence dental caries. Maintaining good oral health could help reduce asthma risk, highlighting the need for integrated oral and respiratory health strategies.

背景:龋齿是一种广泛存在的与全身健康相关的口腔疾病。哮喘是一种慢性气道疾病,会影响生活质量,并可能影响口腔健康。虽然哮喘和龋齿之间的关系尚无定论,但一些研究表明,哮喘会增加龋齿的风险。本研究应用孟德尔随机化(MR)来研究它们之间潜在的因果关系。方法:利用公开的全基因组关联研究(GWAS)数据进行双向磁共振分析。根据三个关键的MR分析假设选择合适的工具变量。采用的主要方法是反方差加权(IVW)方法,辅助方法包括MR- egger回归、加权中位数、简单模式、加权模式以及MR多效性残差和异常值技术。结果:MR分析显示龋病与哮喘呈显著正相关(IVW OR >1, p 0.05)。敏感性分析证实无异质性或多效性,支持这些发现的稳健性。结论:本研究提示龋齿可能促进哮喘的发展,而哮喘并不直接影响龋齿。保持良好的口腔健康有助于降低哮喘风险,强调需要采取综合口腔和呼吸健康战略。
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引用次数: 0
Association Between Oral Diadochokinesis, Grade and Sex in Japanese Elementary School Children: A Cross-Sectional Analysis From the Kuroishi Oral Health Study. 日本小学生口腔发育、年级和性别之间的关系:来自Kuroishi口腔健康研究的横断面分析。
IF 1.9 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-28 DOI: 10.1111/ipd.70069
Kaichi Hayashi, Keishi Sato, Satoru Morishita, Itoyo Tokuda, Keiji Wada, Shintaro Yokoyama, Tsukasa Tanaka, Kaori Sawada, Kei Kurita, Toyoaki Ashida, Koichi Murashita, Tatsuya Mikami, Shigeyuki Nakaji, Wataru Kobayashi

Background: Tongue-lip motor function is essential for speech and swallowing. However, research on oral diadochokinesis (ODK), an indicator of this function, remains limited among Japanese children.

Aim: To provide foundational ODK data in Japanese children and examine its associations with grade, sex and dental and anthropometric variables.

Design: Data from the 2022-2023 Kuroishi Oral Health Study were analysed for 464 third- to sixth-grade students. ODK (/pa/, /ta/, /ka/), grade, sex, total number of teeth, decayed, missing and filled permanent teeth (DMFT) index, and body mass index (BMI) were examined using analysis of variance, t-tests, and multiple regression.

Results: Mean ODK values increased with grade, with sixth-graders showing significantly higher values than third-, fourth- or fifth-graders. Across all syllables, girls showed significantly higher values than boys in fourth or fifth grades, with no significant differences in third or sixth grades. No significant associations were found between ODK and the total number of teeth, DMFT index or BMI.

Conclusion: This study provides foundational ODK data in Japanese children, highlighting grade- and sex-related variations. These findings enhance the understanding of tongue-lip motor function development and may serve as a reference for future research and clinical assessments.

背景:舌唇运动功能对语言和吞咽是必不可少的。然而,关于口腔内分泌功能(ODK)的研究,这一功能的指标,在日本儿童中仍然有限。目的:提供日本儿童的基本ODK数据,并研究其与年级、性别、牙齿和人体测量变量的关系。设计:分析了来自2022-2023年Kuroishi口腔健康研究的464名三至六年级学生的数据。采用方差分析、t检验、多元回归等方法,对ODK (/pa/、/ta/、/ka/)、牙级、性别、牙总数、恒牙蛀牙、缺牙和补牙(DMFT)指数、体重指数(BMI)进行分析。结果:平均ODK值随着年级的增加而增加,六年级的ODK值明显高于三年级、四年级和五年级。在所有音节中,女孩在四年级和五年级表现出明显高于男孩的价值,在三年级和六年级没有显著差异。ODK与牙齿总数、DMFT指数或BMI之间无显著相关性。结论:本研究提供了日本儿童ODK的基础数据,突出了年级和性别相关的差异。这些发现增强了对舌唇运动功能发育的认识,可为今后的研究和临床评估提供参考。
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引用次数: 0
Effects of Preoperative Immersive and Non-Immersive Virtual Reality Exposure on Dental Anxiety in Children: A Randomised Controlled Trial. 术前沉浸式和非沉浸式虚拟现实暴露对儿童牙科焦虑的影响:一项随机对照试验。
IF 1.9 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-22 DOI: 10.1111/ipd.70066
Leezallini Selvaraj, Zamros Yuzadi Mohd Yusof, Nor Nadia Zakaria, Nurul Zeety Azizi, Noorhidayah Zainal Aalam

Background: Preoperative familiarisation using virtual reality (VR) devices before dental treatment is an innovative strategy to manage dental anxiety in children.

Aim: To evaluate the effectiveness of preoperative immersive and non-immersive VR exposure in children with dental anxiety and its correlation with physiological response.

Design: A total of 66 children aged 9-12 years with dental anxiety were randomised into immersive VR exposure (IVRE), non-immersive VR exposure (NIVRE), and control groups. Before receiving a fissure sealant on one permanent molar, IVRE participants navigated a virtual dental clinic, NIVRE participants viewed dental-themed cartoons, and controls waited as usual. Pre- and post-intervention anxiety (Malay-MCDASf) and pulse rate were analysed using ANOVA, paired t-tests, and Pearson's correlation.

Results: Of 66 participants, two dropped out. IVRE and NIVRE significantly reduced dental anxiety compared to control (IVRE vs. Control: p = 0.008; NIVRE vs. Control: p = 0.009), with large effect sizes. No significant differences in PR reductions between groups (p = 0.052, d = 0.09), indicating a small clinical effect. A significant postoperative correlation existed between Malay-MCDASf and PR (r = 0.285, p = 0.022).

Conclusion: VR reduced children's preoperative dental anxiety but did not significantly affect pulse rate. The correlation between self-reported anxiety and physiological response highlights VR's potential as an adjunct in paediatric anxiety management (197 words).

Trial registration: ClinicalTrials.gov identifier: NCT05854329; National Medical Research Register: NMRR ID-23-01114-ATC.

背景:在牙科治疗前使用虚拟现实(VR)设备进行术前熟悉是一种管理儿童牙科焦虑的创新策略。目的:评价术前沉浸式和非沉浸式VR暴露对牙科焦虑患儿的治疗效果及其与生理反应的相关性。设计:66名9-12岁患有牙科焦虑症的儿童随机分为沉浸式虚拟现实暴露组(IVRE)、非沉浸式虚拟现实暴露组(NIVRE)和对照组。在接受恒磨牙缝密封剂之前,IVRE参与者浏览了一个虚拟牙科诊所,NIVRE参与者观看了牙科主题漫画,对照组则像往常一样等待。采用方差分析、配对t检验和Pearson相关分析干预前和干预后的焦虑(malaysia - mcdasf)和脉搏率。结果:66名参与者中,2人退出。与对照组相比,IVRE和NIVRE显著降低了牙齿焦虑(IVRE vs. control: p = 0.008; NIVRE vs. control: p = 0.009),效应量很大。两组间PR降低无显著差异(p = 0.052, d = 0.09),提示临床效果较小。术后mal - mcdasf与PR存在显著相关性(r = 0.285, p = 0.022)。结论:虚拟现实降低了儿童术前牙科焦虑,但对脉搏率无明显影响。自我报告的焦虑和生理反应之间的相关性突出了VR作为儿科焦虑管理辅助手段的潜力。试验注册:ClinicalTrials.gov标识符:NCT05854329;国家医学研究注册:NMRR ID-23-01114-ATC。
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引用次数: 0
An Investigation of the Efficacy of Resin-Based Fissure Sealants in Preventing Caries on Primary Molars. 树脂基牙槽封闭剂预防初生磨牙龋的疗效研究。
IF 1.9 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-15 DOI: 10.1111/ipd.70058
Harleen Kumar, Shanika Nanayakkara, Mohamed Halane, Nicole Azizian, Chaturi Neboda, Rosalyn Sulyanto

Background: The association between light-polymerised resin-based fluoride-releasing sealants and pit-and-fissure caries on primary molars is unclear.

Aim: To investigate the efficacy of resin-based fissure sealants in preventing caries on primary molars.

Design: In this retrospective study of patients attending a tertiary dental hospital for at least 30 months, records of 106 children (275 teeth) were reviewed. Sealant placement on primary molars in the outpatient clinic (OPC) and under general anaesthesia (GA) was recorded, measuring caries incidence over time.

Results: Of the 275 teeth, 94 (34.2%) developed caries during this period. Among those carious teeth, 17 teeth (18.1%) were sealed compared to the 77 (81.9%) non-sealed (p < 0.001). In molars that developed caries, those sealed under GA were associated with longer caries-free mean duration compared to the non-sealed molars (3.07 years compared with 2.32 years, respectively, p < 0.001). Among teeth sealed in OPC, one tooth developed caries. An adjusted hazard ratio of 0.048 (95% CI: 0.025-0.090, p < 0.001) demonstrated a 95.2% lower hazard of caries development in the sealant group compared to the non-sealant group.

Conclusion: Sealed primary molars are less likely to develop pit-and-fissure caries in OPC and GA, with a substantial long-term protective effect observed in the GA-treated group.

背景:光聚合树脂基氟化物释放密封剂与乳牙牙槽和牙槽龋之间的关系尚不清楚。目的:探讨树脂基牙槽封闭剂预防初生磨牙龋的效果。设计:本研究对在某三级牙科医院住院至少30个月的患者进行回顾性研究,回顾了106名儿童(275颗牙齿)的记录。记录在门诊(OPC)和全身麻醉(GA)情况下,在第一磨牙上放置密封剂的情况,测量随时间变化的龋发病率。结果:275颗牙中94颗(34.2%)发生龋病。结果显示,封闭组有17颗牙(18.1%),未封闭组有77颗牙(81.9%)(p)。结论:封闭组和非封闭组的初生磨牙发生坑裂性龋的可能性较低,具有明显的长期保护作用。
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引用次数: 0
Prevalence of Temporomandibular Disorders and Their Association With Facial Biotype in Chilean Children and Adolescents: A Cross-Sectional Study. 智利儿童和青少年颞下颌疾病患病率及其与面部生物型的关系:一项横断面研究。
IF 1.9 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-12 DOI: 10.1111/ipd.70061
Fiorella Zambrano Verduga, Mariana Ramírez Rodríguez, Nicolás Flores Palominos, Gabriel Andrade Cabrera, Claudio Gamboa Vidal

Background: Temporomandibular Disorders (TMD) in children are often under-recognized, with prevalence estimates typically approaching 70% according to recent epidemiological studies. This range complicates interpretation and highlights the need for standardized diagnostic protocols. Facial biotype has been proposed as a potential risk factor, given reported links between craniofacial features and temporomandibular joint alterations, yet pediatric evidence remains limited.

Aim: To determine the prevalence of TMD and its association with facial biotype in Chilean children aged 7-14 years, providing relevant data for early clinical intervention.

Methods: A cross-sectional study evaluated TMD and facial biotypes in 83 participants aged 7-14. Axis I of the DC/TMD adapted for children identified TMD, incorporating recognized diagnostic criteria. Cephalometric analysis using Ricketts' VERT index determined each participant's facial biotype.

Results: The study found a 27.71% TMD prevalence. A significant association was observed between the dolichofacial biotype and articular disorders, specifically disc displacement with reduction and arthralgia. These findings suggest a potential relationship between facial biotype and articular disorders in pediatric populations.

Conclusion: Among Chilean children aged 7-14, TMD prevalence reached 27.71%. Furthermore, the dolichofacial biotype was linked to articular disorders, highlighting the value of recognizing facial patterns to facilitate early intervention.

背景:根据最近的流行病学研究,儿童颞下颌疾病(TMD)的患病率估计通常接近70%,但往往未得到充分认识。这一范围使解释复杂化,并突出了标准化诊断方案的必要性。鉴于颅面特征与颞下颌关节改变之间的联系,面部生物型被认为是一个潜在的危险因素,但儿科证据仍然有限。目的:了解智利7-14岁儿童TMD患病率及其与面部生物型的关系,为早期临床干预提供相关数据。方法:采用横断面研究对83名7-14岁的参与者进行TMD和面部生物型评价。DC/TMD轴I适用于确诊TMD的儿童,纳入公认的诊断标准。使用里基茨VERT指数的头部测量分析确定了每个参与者的面部生物型。结果:研究发现TMD患病率为27.71%。颅面生物型与关节疾病,特别是伴有复位的椎间盘移位和关节痛之间存在显著关联。这些发现表明,在儿童人群中,面部生物类型和关节疾病之间存在潜在的关系。结论:智利7 ~ 14岁儿童TMD患病率为27.71%。此外,面部面部生物型与关节疾病有关,突出了识别面部模式以促进早期干预的价值。
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引用次数: 0
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International journal of paediatric dentistry
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