Xi Wang, Manyu Zhang, Jixiu Liu, Yixin Wang, Qi Liu, Hong Ye
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引用次数: 0
Abstract
Background: Acute Lymphoblastic Leukemia (ALL) in children is associated with diverse symptoms affecting quality of life and treatment efficacy. This study aimed to evaluate symptom progression in children with ALL to inform targeted interventions.
Methods: We assessed children with ALL from January 2023 to June 2024 using the Memorial Symptom Assessment Scale for Children (MSAS-C) at different chemotherapy stages.
Results: A total of 102 children were included and they experienced an average of 15.52 symptoms. Initially, three symptom clusters predominated: emotional, gastrointestinal, and somatic. As chemotherapy advanced through induction and consolidation phases, the symptom profile expanded to include neurological, self-image disturbance, and skin and mucosal symptoms. During the maintenance phase, the clusters were emotional, gastrointestinal, somatic, neurological, and self-image disturbance.
Conclusion: Symptom clusters in pediatric ALL patients change dynamically with chemotherapy phases, highlighting the need for meticulous assessment tailored interventions to enhance clinical management and patient care.
期刊介绍：
The Journal of Pediatric Health Care, the official journal of the National Association of Pediatric Nurse Practitioners, provides scholarly clinical information and research regarding primary, acute and specialty health care for children of newborn age through young adulthood within a family-centered context. The Journal disseminates multidisciplinary perspectives on evidence-based practice and emerging policy, advocacy and educational issues that are of importance to all healthcare professionals caring for children and their families.
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