Predicting discharge destination and length of stay after open reduction internal fixation of distal femur fractures.

Akash A Shah, Brian K Zukotynski, Chohee Kim, Brendan Y Shi, Changhee Lee, Sai K Devana, Alexander Upfill-Brown, Erik N Mayer, Nelson F SooHoo, Christopher Lee
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Abstract

Introduction: Prediction of nonhome discharge after open reduction internal fixation (ORIF) of distal femur fractures may facilitate earlier discharge planning, potentially decreasing costs and improving outcomes. We aim to develop algorithms predicting nonhome discharge and time to discharge after distal femur ORIF and identify features important for model performance.

Methods: This is a retrospective cohort study of adults in the American College of Surgeons National Surgical Quality Improvement Program database who underwent distal femur ORIF between 2010 and 2019. The primary outcome was nonhome discharge, and the secondary outcome was time to nonhome discharge. We developed logistic regression and machine learning models for prediction of nonhome discharge. We developed an ensemble machine learning-driven survival model to predict discharge within 3, 5, and 7 days.

Results: Of the 5330 patients included, 3772 patients were discharged to either a skilled nursing facility or rehabilitation hospital after index ORIF. Of all tested models, the logistic regression algorithm was the best-performing model and well calibrated. The ensemble model predicts discharge within 3, 5, and 7 days with fair discrimination. The following features were the most important for model performance: inpatient status, American Society of Anesthesiology classification, preoperative functional status, wound status, medical comorbidities, age, body mass index, and preoperative laboratory values.

Conclusion: We report a well-calibrated algorithm that accurately predicts nonhome discharge after distal femur ORIF. In addition, we report an ensemble survival algorithm predicting time to nonhome discharge. Accurate preoperative prediction of discharge destination may facilitate earlier discharge, reducing the costs and complications associated with prolonged hospitalization.

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预测股骨远端骨折切开复位内固定后的出院目的地和住院时间。
导言:预测股骨远端骨折切开复位内固定(ORIF)后的非家庭出院可能有助于早期出院计划,潜在地降低成本并改善预后。我们的目标是开发预测股骨远端ORIF后非家庭放电和放电时间的算法,并识别对模型性能重要的特征。方法:这是一项回顾性队列研究,研究对象是2010年至2019年期间接受股骨远端ORIF手术的美国外科学会国家手术质量改进计划数据库中的成年人。主要观察指标为非家庭出院,次要观察指标为到非家庭出院的时间。我们开发了逻辑回归和机器学习模型来预测非家庭出院。我们开发了一个集成机器学习驱动的生存模型来预测3、5和7天内的放电情况。结果:在纳入的5330例患者中,3772例患者在指数ORIF后出院至专业护理机构或康复医院。在所有测试的模型中,逻辑回归算法是表现最好的模型,并且校准良好。集合模型对3、5和7天内的流量进行了预测,并具有公平的歧视。以下特征对模型性能最重要:住院情况、美国麻醉学会分类、术前功能状况、伤口状况、医疗合并症、年龄、体重指数和术前实验室值。结论:我们报告了一种校准良好的算法,可以准确预测股骨远端ORIF术后的非家庭放电。此外,我们报告了一个预测非家庭出院时间的集成生存算法。术前对出院目的地的准确预测有助于提前出院,减少住院时间延长带来的费用和并发症。
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