Cost-effectiveness of diabetes screening and diagnosis services for people with TB in the Philippines

IF 7.4 3区 医学 Q1 ENDOCRINOLOGY & METABOLISM Diabetes research and clinical practice Pub Date : 2025-03-08 DOI:10.1016/j.diabres.2025.112085
Takuya Yamanaka , Mary Christine Castro , Sharon E. Cox , Yoko V. Laurence , Anna Vassall
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Abstract

Aim

Tuberculosis (TB) remains a leading cause of death in low- and middle-income countries, and diabetes is a known risk factor for progression to active TB disease. While the Philippines national strategic plan for TB aims to screen 90 % of TB cases for diabetes, the cost-effectiveness of screening is not well known.

Methods

We constructed a decision tree model to assess the cost-effectiveness of providing diabetes testing for 90% of people with an unknown diabetes status at their TB diagnosis and subsequent routine diabetes care, compared to the scenario of providing TB treatment only. Cost-effectiveness of the intervention was assessed from the provider and societal perspectives.

Results

The intervention was cost saving. At a willingness to pay threshold per disability-adjusted-life-year of 50 % of gross domestic product per capita, the probability of the intervention being cost saving was 99 % from the provider and societal perspectives in people aged ≥18 years. The probability was highest in people with BMI >18.5 kg/m2 and in those aged >45 years.

Conclusion

Our findings suggest that providing diabetes care for people with TB will be cost saving, and the intervention is likely to be most cost saving in people with BMI >18.5 kg/m2 or those aged >45 years.
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菲律宾肺结核患者糖尿病筛查和诊断服务的成本效益。
目的:结核病(TB)仍然是低收入和中等收入国家的主要死亡原因,而糖尿病是进展为活动性结核病的已知危险因素。虽然菲律宾结核病国家战略计划的目标是对90% %的结核病病例进行糖尿病筛查,但筛查的成本效益尚不清楚。方法:我们构建了一个决策树模型来评估在结核病诊断和随后的常规糖尿病护理中为90%的未知糖尿病患者提供糖尿病检测的成本效益,与仅提供结核病治疗的情况相比。从提供者和社会的角度评估了干预的成本效益。结果:该干预措施节省了成本。在每个残疾调整生命年的支付意愿阈值为人均国内生产总值的50% %时,从提供者和社会的角度来看,在≥18 岁的人群中,干预节省成本的概率为99 %。BMI指数为b>8.5的人和年龄为bbbb45 岁的人患糖尿病的可能性最高。结论:我们的研究结果表明,为结核病患者提供糖尿病护理将节省成本,并且对BMI为18.5 kg/m2或年龄为45 岁的人群进行干预可能最节省成本。
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来源期刊
Diabetes research and clinical practice
Diabetes research and clinical practice 医学-内分泌学与代谢
CiteScore
10.30
自引率
3.90%
发文量
862
审稿时长
32 days
期刊介绍: Diabetes Research and Clinical Practice is an international journal for health-care providers and clinically oriented researchers that publishes high-quality original research articles and expert reviews in diabetes and related areas. The role of the journal is to provide a venue for dissemination of knowledge and discussion of topics related to diabetes clinical research and patient care. Topics of focus include translational science, genetics, immunology, nutrition, psychosocial research, epidemiology, prevention, socio-economic research, complications, new treatments, technologies and therapy.
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