Glucose-insulin regulatory system: Chaos control and stability analysis via Atangana–Baleanu fractal-fractional derivatives

IF 6.8 2区 工程技术 Q1 ENGINEERING, MULTIDISCIPLINARY alexandria engineering journal Pub Date : 2025-03-12 DOI:10.1016/j.aej.2025.02.066
Muflih Alhazmi , Sayed Saber
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Abstract

This study explores the glucose-insulin regulatory system using a fractal-fractional framework based on the Atangana–Baleanu derivative. By formulating a set of differential equations incorporating the Atangana–Baleanu fractal-fractional derivative, we capture the intricate, nonlinear dynamics of glucose and insulin. This is with enhanced accuracy compared to traditional models. We establish the existence and uniqueness of solutions through fixed-point theory and analyze Hyers–Ulam stability. Moreover, we employ a linear controller to stabilize chaotic behavior in the system, mitigating fluctuations that can lead to erratic physiological responses. Both analytical and numerical results validate the model’s robustness to representing physiological processes. Our findings demonstrate that the fractal-fractional model significantly improves glucose-insulin dynamics modeling, highlighting its potential as a powerful tool for diabetes management and prediction of complex biological behaviors.
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葡萄糖-胰岛素调节系统:基于Atangana-Baleanu分形-分数阶导数的混沌控制与稳定性分析
本研究使用基于Atangana-Baleanu衍生物的分形-分数框架探索葡萄糖-胰岛素调节系统。通过建立一组包含Atangana-Baleanu分形-分数阶导数的微分方程,我们捕捉到了葡萄糖和胰岛素复杂的非线性动力学。与传统模型相比,这具有更高的准确性。利用不动点理论建立了解的存在唯一性,并分析了Hyers-Ulam稳定性。此外,我们采用线性控制器来稳定系统中的混沌行为,减轻可能导致不稳定生理反应的波动。分析和数值结果验证了该模型对生理过程的鲁棒性。我们的研究结果表明,分形-分数模型显著改善了葡萄糖-胰岛素动力学建模,突出了其作为糖尿病管理和预测复杂生物行为的强大工具的潜力。
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来源期刊
alexandria engineering journal
alexandria engineering journal Engineering-General Engineering
CiteScore
11.20
自引率
4.40%
发文量
1015
审稿时长
43 days
期刊介绍: Alexandria Engineering Journal is an international journal devoted to publishing high quality papers in the field of engineering and applied science. Alexandria Engineering Journal is cited in the Engineering Information Services (EIS) and the Chemical Abstracts (CA). The papers published in Alexandria Engineering Journal are grouped into five sections, according to the following classification: • Mechanical, Production, Marine and Textile Engineering • Electrical Engineering, Computer Science and Nuclear Engineering • Civil and Architecture Engineering • Chemical Engineering and Applied Sciences • Environmental Engineering
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