Mast cell leukemia: a rare case report and literature review.

IF 3.5 3区 医学 Q2 ONCOLOGY Frontiers in Oncology Pub Date : 2025-02-25 eCollection Date: 2025-01-01 DOI:10.3389/fonc.2025.1537301
Lu Tian, Xiang Yan, Shaodan Tian, Yang Shen, Qiuyue Fan
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Abstract

Mast cell leukemia (MCL) is an extremely rare and aggressive hematologic malignancy, characterized by a poor prognosis and short survival. Currently, no standardized treatment guidelines have been established. This study presents the clinical data of a patient with primary MCL accompanied by C-findings, and analyzes the clinical features, diagnostic challenges, and therapeutic approaches for this disease through a comprehensive review of the relevant literature. Furthermore, the study discusses current perspectives on research developments in MCL. By increasing clinical awareness of MCL, this work aims to provide valuable insights and references for clinicians in the diagnosis and management of this challenging condition.

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肥大细胞白血病1例报告及文献复习。
肥大细胞白血病(MCL)是一种极其罕见的侵袭性血液系统恶性肿瘤,其特点是预后差,生存期短。目前,还没有制定标准化的治疗指南。本研究报告了1例原发性MCL伴C-findings患者的临床资料,并通过对相关文献的综合复习,分析了该病的临床特点、诊断挑战和治疗方法。此外,该研究还讨论了MCL研究发展的当前观点。通过提高临床对MCL的认识,本研究旨在为临床医生在诊断和治疗这一具有挑战性的疾病方面提供有价值的见解和参考。
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来源期刊
Frontiers in Oncology
Frontiers in Oncology Biochemistry, Genetics and Molecular Biology-Cancer Research
CiteScore
6.20
自引率
10.60%
发文量
6641
审稿时长
14 weeks
期刊介绍: Cancer Imaging and Diagnosis is dedicated to the publication of results from clinical and research studies applied to cancer diagnosis and treatment. The section aims to publish studies from the entire field of cancer imaging: results from routine use of clinical imaging in both radiology and nuclear medicine, results from clinical trials, experimental molecular imaging in humans and small animals, research on new contrast agents in CT, MRI, ultrasound, publication of new technical applications and processing algorithms to improve the standardization of quantitative imaging and image guided interventions for the diagnosis and treatment of cancer.
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