Acute Effect of Moderate-Intensity Interval Intradialytic Exercise on Cerebral Oxygenation in Hemodialysis Patients: A Randomized Crossover Trial.

IF 9.4 1区 医学 Q1 UROLOGY & NEPHROLOGY Journal of The American Society of Nephrology Pub Date : 2025-03-12 DOI:10.1681/ASN.0000000672
Sho Kojima, Naoto Usui, Akimi Uehata, Akihito Inatsu, Yasuo Chiba, Hideki Hisadome, Yusuke Suzuki, Junichiro Nakata, Atsuhiro Tsubaki
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中等强度间歇分析性运动对血液透析患者脑氧合的急性影响:一项随机交叉试验。
背景:血液透析(HD)患者的认知功能障碍与区域脑氧合(rSO2)降低有关。分析性运动改善认知功能;尽管如此,分析内运动对脑循环的急性影响尚不清楚。本研究旨在评估透析期间透析内运动对rSO2的急性影响。方法:这项单中心、开放标签、随机交叉试验纳入了20例HD患者。患者按随机顺序接受常规护理对照组和透析内运动组。分析内运动条件包括35分钟的无氧阈值强度间歇运动的表现。在HD期间,使用近红外光谱测量前额叶皮层的脑氧合(rSO2、含氧血红蛋白、脱氧血红蛋白和总血红蛋白)。心血管反应,包括心率、心脏指数、平均动脉压和血气,也被评估。采用双向重复测量方差分析对两种情况进行比较。结果:分析纳入16例患者,其中4例因脑氧合数据存在伪影而被排除。结论:透析时运动可显著提高透析前后的rSO2,改善程度与透析前相同。
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来源期刊
Journal of The American Society of Nephrology
Journal of The American Society of Nephrology 医学-泌尿学与肾脏学
CiteScore
22.40
自引率
2.90%
发文量
492
审稿时长
3-8 weeks
期刊介绍: The Journal of the American Society of Nephrology (JASN) stands as the preeminent kidney journal globally, offering an exceptional synthesis of cutting-edge basic research, clinical epidemiology, meta-analysis, and relevant editorial content. Representing a comprehensive resource, JASN encompasses clinical research, editorials distilling key findings, perspectives, and timely reviews. Editorials are skillfully crafted to elucidate the essential insights of the parent article, while JASN actively encourages the submission of Letters to the Editor discussing recently published articles. The reviews featured in JASN are consistently erudite and comprehensive, providing thorough coverage of respective fields. Since its inception in July 1990, JASN has been a monthly publication. JASN publishes original research reports and editorial content across a spectrum of basic and clinical science relevant to the broad discipline of nephrology. Topics covered include renal cell biology, developmental biology of the kidney, genetics of kidney disease, cell and transport physiology, hemodynamics and vascular regulation, mechanisms of blood pressure regulation, renal immunology, kidney pathology, pathophysiology of kidney diseases, nephrolithiasis, clinical nephrology (including dialysis and transplantation), and hypertension. Furthermore, articles addressing healthcare policy and care delivery issues relevant to nephrology are warmly welcomed.
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