Surgery in patients aged ≥ 80 years: mortality and recovery in a nationwide cohort study*

IF 6.9 1区 医学 Q1 ANESTHESIOLOGY Anaesthesia Pub Date : 2025-03-12 DOI:10.1111/anae.16580
Jesper Eriksson, Cornelia Sandberg, Naima Kilhamn, Max Bell, Anders Oldner, Emma Larsson
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Abstract

Introduction

As the global population ages, the demand for surgical interventions in older adults is rising. Older patients face increased risks due to age-related physiological changes and comorbidities, making surgery and postoperative care challenging. This study aimed to assess short- and long-term mortality, as well as patient-centred outcomes such as days alive and at home 30 and 90 days after surgery, in patients aged ≥ 80 y undergoing surgical procedures.

Methods

This nationwide cohort study utilised data from the Swedish Perioperative Register, including surgeries in patients aged ≥ 80 y in Sweden from January 2019 to March 2023. We linked peri-operative data with the National Patient Register for comorbidities and with the National Cause of Death Register. The primary outcome was all-cause 30-day mortality, with secondary outcomes of 365-day mortality and days alive and at home 30 and 90 days after surgery.

Results

A total of 118,359 patients were included, with 54,320 undergoing elective and 64,039 acute surgeries. Thirty-day mortality was 1.2% for elective and 9.9% for acute surgeries. Mortality increased significantly with age, particularly for patients aged ≥ 90 y compared with those aged 80–84 y. Days alive and at home 30 and 90 days after surgery were significantly lower for acute surgery patients, indicating longer recovery times and more postoperative complications.

Discussion

Older adults, especially those aged ≥ 90 y, experience high mortality and significant challenges in postoperative recovery after acute surgeries. Elective surgeries are associated with lower short-term mortality, suggesting that age alone should not preclude surgical interventions. Tailored peri-operative care and patient-centred decision-making are essential to improve outcomes in this vulnerable population.

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年龄≥ 80 岁患者的外科手术:全国队列研究中的死亡率和康复情况*
随着全球人口老龄化,老年人手术干预的需求正在上升。由于年龄相关的生理变化和合并症,老年患者面临更高的风险,使手术和术后护理具有挑战性。本研究旨在评估≥80岁接受外科手术的患者的短期和长期死亡率,以及以患者为中心的结局,如手术后30天和90天的存活天数和在家天数。方法:这项全国性队列研究利用了瑞典围手术期登记的数据,包括2019年1月至2023年3月期间瑞典年龄≥80岁的患者的手术。我们将围手术期数据与国家合并症患者登记册和国家死因登记册联系起来。主要终点为全因30天死亡率,次要终点为手术后30天和90天的365天死亡率、存活和在家天数。结果共纳入患者118359例,其中择期手术54320例,急性手术64039例。择期手术30天死亡率为1.2%,急性手术为9.9%。与80-84岁的患者相比,年龄≥90岁的患者死亡率明显增加。急性手术患者术后30天和90天的存活天数和在家天数明显较低,这表明恢复时间较长,术后并发症较多。老年人,特别是年龄≥90岁的老年人,急性手术后的死亡率高,术后恢复面临重大挑战。选择性手术与较低的短期死亡率相关,表明年龄不应单独排除手术干预。量身定制的围手术期护理和以患者为中心的决策对于改善这一弱势群体的预后至关重要。
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来源期刊
Anaesthesia
Anaesthesia 医学-麻醉学
CiteScore
21.20
自引率
9.30%
发文量
300
审稿时长
6 months
期刊介绍: The official journal of the Association of Anaesthetists is Anaesthesia. It is a comprehensive international publication that covers a wide range of topics. The journal focuses on general and regional anaesthesia, as well as intensive care and pain therapy. It includes original articles that have undergone peer review, covering all aspects of these fields, including research on equipment.
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