Percutaneous gastric embolization for obesity: A prospective mid-term outcomes study

Medicina clinica (English ed.) Pub Date : 2025-03-14 Epub Date: 2025-02-24 DOI:10.1016/j.medcle.2024.09.019
Carlos Ivan Soledispa Suárez , Robert Alarcón Cedeño , Luis Mariano de la Torre Fonseca , Stephanie Susana Alberca Bonilla , Fabiola Loor Cedeño , Mayra Elizabeth Briones Fajardo , Pablo Juan-Salvadores
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Abstract

Introduction

Obesity represents one of the most pressing public health challenges that needs to be solved globally, with serious health implications. Despite primary prevention efforts the prevalence of obesity continues to increase. Percutaneous gastric embolisation (PGE) has emerged as a promising technique in the management of this disease.

Material and methods

Prospective longitudinal cohort study including 15 patients diagnosed with grade III obesity, admitted to the Haemodynamics Service of the Cardiovascular Health Institute during the year 2022.

Results

86.7% of the PGEs were successful. Treated patients experienced significant weight loss when comparing baseline weight (101.2 ± 23.0 SE = 5.9) with weight at 6 months after the interventional procedure (91.5 ± 19.8, SE = 5.1) t (14) = 5.3, p < 0.001, d = 0.45. Especially males (106.7 ± 18.4, p = 0.01). No major vascular complications, gastric ulcer or ischaemia, or abdominal symptoms were documented in any of the patients included in the study. Only 6 patients (40%) presented with epigastralgia, 9 (60%) with nausea and 3 (20%) with vomiting.

Conclusions

Percutaneous gastric embolisation is an effective and safe procedure to reduce BMI with a high success rate, well tolerated by obese patients, without major complications, whose results are maintained over time.
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经皮胃栓塞治疗肥胖:一项前瞻性中期结果研究
肥胖是全球需要解决的最紧迫的公共卫生挑战之一,具有严重的健康影响。尽管采取了初级预防措施,但肥胖的患病率仍在继续上升。经皮胃栓塞术(PGE)已成为一种很有前途的治疗这种疾病的技术。材料与方法前瞻性纵向队列研究,纳入2015年心血管健康研究所血流动力学服务部收治的15例确诊为III级肥胖患者。结果86.7%的PGEs成功。基线体重(101.2±23.0 SE = 5.9)与介入手术后6个月的体重(91.5±19.8,SE = 5.1)相比,接受治疗的患者出现了显著的体重减轻;0.001, d = 0.45。男性(106.7±18.4,p = 0.01)。研究中所有患者均未出现重大血管并发症、胃溃疡或缺血或腹部症状。仅6例(40%)出现上腹痛,9例(60%)出现恶心,3例(20%)出现呕吐。结论经皮胃栓塞术是一种安全有效的降低BMI的方法,成功率高,肥胖患者耐受性好,无重大并发症,效果长期稳定。
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