Chiral helical peptide nanomaterials: Construction strategies and applications

IF 13.2 1区 材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY Nano Today Pub Date : 2025-03-13 DOI:10.1016/j.nantod.2025.102703
Shiwei Wang , Zhen He , Xiaolin Duan , Lulu He , Jie Xing , Aiguo Wu , Juan Li
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引用次数: 0

Abstract

Chiral helical nanostructures exhibit tunable functionalities in both chemical and biological fields. The intrinsic chirality of amino acids and the tunable supramolecular assembly capabilities of peptides make them ideal materials for constructing and investigating chiral helical peptide nanomaterials (CHPNs). By employing flexible design strategies that manipulate the chirality of amino acids, peptide sequences, and environmental factors, CHPNs can further leverage the supramolecular chirality to expand their potential properties for applications. This review delves into the latest advancements in the design and comprehensive regulation of CHPNs through diverse factors, including pH, solvents, temperatures, ions, and external molecules. Additionally, the review provides an overview of the broad application prospects of CHPNs in drug delivery, antibacterial therapy, cell regulation, chiral recognition, and catalysis, with a particular emphasis on the functionalities induced by the chiral helical nanostructures.
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来源期刊
Nano Today
Nano Today 工程技术-材料科学:综合
CiteScore
21.50
自引率
3.40%
发文量
305
审稿时长
40 days
期刊介绍: Nano Today is a journal dedicated to publishing influential and innovative work in the field of nanoscience and technology. It covers a wide range of subject areas including biomaterials, materials chemistry, materials science, chemistry, bioengineering, biochemistry, genetics and molecular biology, engineering, and nanotechnology. The journal considers articles that inform readers about the latest research, breakthroughs, and topical issues in these fields. It provides comprehensive coverage through a mixture of peer-reviewed articles, research news, and information on key developments. Nano Today is abstracted and indexed in Science Citation Index, Ei Compendex, Embase, Scopus, and INSPEC.
期刊最新文献
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