Near-infrared carbon dots: pioneering emerging frontiers in biomedical applications

IF 5.7 3区材料科学 Q2 Materials Science New Carbon Materials Pub Date : 2025-02-01 DOI:10.1016/S1872-5805(25)60946-2

Qian HE , Yan-li YANG , Rui-jiao LI, Dan MA, Li-yun ZHANG

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Abstract

Carbon dots (CDs) are fluorescent carbon-based nanomaterials with sizes smaller than 10 nm, that are renowned for their exceptional properties, including superior antiphotobleaching, excellent biocompatibility, and minimal toxicity, which have received significant interest. Near-infrared (NIR) light has emerged as an ideal light source in the biological field due to its advantages of minimal scattering and absorption, long wavelength emission, increased tissue penetration, and reduced interference from biological backgrounds. CDs with efficient absorption and/or emission characteristics in the NIR spectrum have shown remarkable promise in the biomedical uses. This study provides a comprehensive overview of the preparation methods and wavelength modulation strategies for near-infrared CDs and reviews research progress in their use in the areas of biosensing, bioimaging, and therapy. It also discusses current challenges and clinical prospects, aimed at deepening our understanding of the subject and promoting further advances in this field.

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来源期刊

New Carbon Materials MATERIALS SCIENCE, MULTIDISCIPLINARY-

CiteScore

6.10

自引率

8.80%

发文量

3245

审稿时长

5.5 months

期刊介绍： New Carbon Materials is a scholarly journal that publishes original research papers focusing on the physics, chemistry, and technology of organic substances that serve as precursors for creating carbonaceous solids with aromatic or tetrahedral bonding. The scope of materials covered by the journal extends from diamond and graphite to a variety of forms including chars, semicokes, mesophase substances, carbons, carbon fibers, carbynes, fullerenes, and carbon nanotubes. The journal's objective is to showcase the latest research findings and advancements in the areas of formation, structure, properties, behaviors, and technological applications of carbon materials. Additionally, the journal includes papers on the secondary production of new carbon and composite materials, such as carbon-carbon composites, derived from the aforementioned carbons. Research papers on organic substances will be considered for publication only if they have a direct relevance to the resulting carbon materials.