Predictive Limitations of the Geriatric Trauma Outcome Score: A Retrospective Analysis of Mortality in Elderly Patients with Multiple Traumas and Severe Traumatic Brain Injury.

IF 3.3 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Diagnostics Pub Date : 2025-02-28 DOI:10.3390/diagnostics15050586
Sebeom Jeon, Gil Jae Lee, Mina Lee, Kang Kook Choi, Seung Hwan Lee, Jayun Cho, Byungchul Yu
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Abstract

Background/Objectives: The Geriatric Trauma Outcome Score (GTOS) is used to predict in-hospital mortality in geriatric patients with trauma. However, its applicability to elderly patients with multiple traumas and severe traumatic brain injury (TBI) remains poorly understood. This study aimed to evaluate the predictive accuracy of the GTOS in elderly patients with multiple traumas and TBI and assess its performance in patients with mild and severe TBI. Methods: We retrospectively analyzed 1283 geriatric multiple trauma patients (aged ≥ 65 years) treated at a regional trauma center from 2019 to 2023. Patients were stratified into mild (head Abbreviated Injury Scale [AIS] ≤ 3) and severe (head AIS ≥ 4) TBI groups. GTOS values were calculated for each patient, and predicted mortality was compared with in-hospital mortality. GTOS predictive accuracy was assessed by analyzing the receiver operating characteristic curve. Results: Patients had a median Injury Severity Score of 18 (interquartile range: 10-25); 33.3% of patients received red blood cell transfusions within 24 h. The overall in-hospital mortality rate was 17.9%; GTOS predicted a mortality rate of 17.6% ± 0.17. The GTOS accurately predicted the in-hospital mortality in the entire cohort, achieving an Area Under the Curve (AUC) of 0.798. Predictive accuracy diminished for patients with severe TBI (AUC = 0.657), underestimating actual mortality (39.5% vs. 28.8% predicted). Conclusions: While the GTOS remains a useful tool for predicting in-hospital mortality in elderly patients with multiple traumas, it consistently underestimates mortality risk in those with severe TBI. Therefore, applying the GTOS in this patient subgroup warrants careful consideration.

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老年创伤结局评分的预测局限性:对老年多发创伤和严重创伤性脑损伤患者死亡率的回顾性分析。
背景/目的:老年创伤结局评分(GTOS)用于预测老年创伤患者的住院死亡率。然而,其在老年多发和重度创伤性脑损伤(TBI)患者中的适用性尚不清楚。本研究旨在评估GTOS在老年多发创伤合并TBI患者中的预测准确性,并评估其在轻度和重度TBI患者中的表现。方法:回顾性分析2019年至2023年在某区域创伤中心治疗的1283例老年多发创伤患者(年龄≥65岁)。将患者分为轻度(头部简易损伤量表[AIS]≤3)和重度(头部AIS≥4)脑损伤组。计算每位患者的GTOS值,并将预测死亡率与住院死亡率进行比较。通过分析接收机工作特性曲线,评估GTOS预测精度。结果:患者损伤严重程度评分中位数为18(四分位数范围:10-25);24 h内接受红细胞输注的占33.3%,住院总死亡率为17.9%;GTOS预测死亡率为17.6%±0.17。GTOS准确预测了整个队列的住院死亡率,曲线下面积(AUC)为0.798。严重TBI患者的预测准确性降低(AUC = 0.657),低估了实际死亡率(39.5%对28.8%的预测)。结论:虽然GTOS仍然是预测多重创伤老年患者住院死亡率的有用工具,但它始终低估了严重TBI患者的死亡风险。因此,在该患者亚组中应用GTOS值得慎重考虑。
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来源期刊
Diagnostics
Diagnostics Biochemistry, Genetics and Molecular Biology-Clinical Biochemistry
CiteScore
4.70
自引率
8.30%
发文量
2699
审稿时长
19.64 days
期刊介绍: Diagnostics (ISSN 2075-4418) is an international scholarly open access journal on medical diagnostics. It publishes original research articles, reviews, communications and short notes on the research and development of medical diagnostics. There is no restriction on the length of the papers. Our aim is to encourage scientists to publish their experimental and theoretical research in as much detail as possible. Full experimental and/or methodological details must be provided for research articles.
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