Impact of surgical site infection on short- and long-term outcomes of robot-assisted rectal cancer surgery: a two-center retrospective study.

IF 2.5 3区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY International Journal of Colorectal Disease Pub Date : 2025-03-12 DOI:10.1007/s00384-025-04842-9
Shuangming Lin, Hao Zeng, Xiaojie Wang, Xueyi Xue, Yushuo Chen, Baodong Liao, Ying Huang, Dongbo Xu, Pan Chi
{"title":"Impact of surgical site infection on short- and long-term outcomes of robot-assisted rectal cancer surgery: a two-center retrospective study.","authors":"Shuangming Lin, Hao Zeng, Xiaojie Wang, Xueyi Xue, Yushuo Chen, Baodong Liao, Ying Huang, Dongbo Xu, Pan Chi","doi":"10.1007/s00384-025-04842-9","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>Robot-assisted surgery has increasingly gained recognition in the treatment of rectal cancer. This study aimed to assess the incidence of surgical site infection (SSI) that underwent robot-assisted radical rectal cancer surgery and to evaluate their influence on patient outcomes.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 360 patients who underwent robot-assisted radical rectal cancer surgery between 2017 and 2024 at Fujian Medical University Union Hospital and Longyan First Affiliated Hospital of Fujian Medical University. The patients were categorized into surgical site infection and non-surgical site infection groups based on the presence of surgical site infection. Baseline clinicopathological characteristics, perioperative details, and follow-up data were analyzed. Univariate and multivariate logistic regression analyses were performed to identify independent predictors of surgical site infection, and Cox proportional hazards regression models were utilized to evaluate factors influencing overall survival.</p><p><strong>Results: </strong>The study found that 44 out of 360 patients (12.2%) developed surgical site infection. Multivariate analysis indicated that positive perineural invasion (OR 3.59, 95% CI 1.50-8.62, P = 0.004) is an independent risk factor for SSI. Low anterior resection (OR 0.26, 95% CI 0.09-0.73, P = 0.011), preservation of the left colonic artery (OR 0.20, 95% CI 0.09-0.44, P < 0.001), and neoadjuvant therapy (OR 0.45, 95% CI 0.23-0.89, P = 0.021) were associated with reduced risks of SSI. The presence of SSI was significantly associated with a reduction in overall survival (HR 3.43, 95% CI 1.30-9.04, P = 0.012). The risk of developing surgical site infection increases with the number of risk factors, and patients with two or more risk factors have a much higher risk of developing SSI.</p><p><strong>Conclusions: </strong>This study identified perineural invasion as an independent risk factor for the development of SSI that underwent robot-assisted radical rectal cancer surgery. Low anterior resection, preservation of the left colonic artery, and neoadjuvant therapy emerged as protective factors. Moreover, the presence of surgical site infection was significantly correlated with poorer overall survival.</p>","PeriodicalId":13789,"journal":{"name":"International Journal of Colorectal Disease","volume":"40 1","pages":"64"},"PeriodicalIF":2.5000,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Colorectal Disease","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00384-025-04842-9","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Purpose: Robot-assisted surgery has increasingly gained recognition in the treatment of rectal cancer. This study aimed to assess the incidence of surgical site infection (SSI) that underwent robot-assisted radical rectal cancer surgery and to evaluate their influence on patient outcomes.

Methods: A retrospective analysis was conducted on 360 patients who underwent robot-assisted radical rectal cancer surgery between 2017 and 2024 at Fujian Medical University Union Hospital and Longyan First Affiliated Hospital of Fujian Medical University. The patients were categorized into surgical site infection and non-surgical site infection groups based on the presence of surgical site infection. Baseline clinicopathological characteristics, perioperative details, and follow-up data were analyzed. Univariate and multivariate logistic regression analyses were performed to identify independent predictors of surgical site infection, and Cox proportional hazards regression models were utilized to evaluate factors influencing overall survival.

Results: The study found that 44 out of 360 patients (12.2%) developed surgical site infection. Multivariate analysis indicated that positive perineural invasion (OR 3.59, 95% CI 1.50-8.62, P = 0.004) is an independent risk factor for SSI. Low anterior resection (OR 0.26, 95% CI 0.09-0.73, P = 0.011), preservation of the left colonic artery (OR 0.20, 95% CI 0.09-0.44, P < 0.001), and neoadjuvant therapy (OR 0.45, 95% CI 0.23-0.89, P = 0.021) were associated with reduced risks of SSI. The presence of SSI was significantly associated with a reduction in overall survival (HR 3.43, 95% CI 1.30-9.04, P = 0.012). The risk of developing surgical site infection increases with the number of risk factors, and patients with two or more risk factors have a much higher risk of developing SSI.

Conclusions: This study identified perineural invasion as an independent risk factor for the development of SSI that underwent robot-assisted radical rectal cancer surgery. Low anterior resection, preservation of the left colonic artery, and neoadjuvant therapy emerged as protective factors. Moreover, the presence of surgical site infection was significantly correlated with poorer overall survival.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
求助全文
约1分钟内获得全文 去求助
来源期刊
CiteScore
4.90
自引率
3.60%
发文量
206
审稿时长
3-8 weeks
期刊介绍: The International Journal of Colorectal Disease, Clinical and Molecular Gastroenterology and Surgery aims to publish novel and state-of-the-art papers which deal with the physiology and pathophysiology of diseases involving the entire gastrointestinal tract. In addition to original research articles, the following categories will be included: reviews (usually commissioned but may also be submitted), case reports, letters to the editor, and protocols on clinical studies. The journal offers its readers an interdisciplinary forum for clinical science and molecular research related to gastrointestinal disease.
期刊最新文献
Evaluating organ preservation strategies versus radical surgery in T2N0 rectal cancer: survival outcomes and tumor size impact. Association of radiotherapy with secondary pelvic cancers in male patients with rectal cancer. Impact of surgical site infection on short- and long-term outcomes of robot-assisted rectal cancer surgery: a two-center retrospective study. Mucosal advancement flap versus ligation of the inter-sphincteric fistula tract for management of trans-sphincteric perianal fistulas in the elderly: a retrospective study. Robotic proctocolectomy with ileal pouch-anal anastomosis: a hybrid approach.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1