Computer-assisted stereoelectroencephalography planning: center-specific priors enhance planning.

IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Frontiers in Neurology Pub Date : 2025-02-27 eCollection Date: 2025-01-01 DOI:10.3389/fneur.2025.1514442
Debayan Dasgupta, Cameron A Elliott, Aidan G O'Keeffe, Roman Rodionov, Kuo Li, Vejay N Vakharia, Farhan A Mirza, M Zubair Tahir, Martin M Tisdall, Anna Miserocchi, Andrew W McEvoy, Sebastien Ourselin, Rachel E Sparks, John S Duncan
{"title":"Computer-assisted stereoelectroencephalography planning: center-specific priors enhance planning.","authors":"Debayan Dasgupta, Cameron A Elliott, Aidan G O'Keeffe, Roman Rodionov, Kuo Li, Vejay N Vakharia, Farhan A Mirza, M Zubair Tahir, Martin M Tisdall, Anna Miserocchi, Andrew W McEvoy, Sebastien Ourselin, Rachel E Sparks, John S Duncan","doi":"10.3389/fneur.2025.1514442","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to refine computer-assisted planning (CAP) of SEEG implantations by adding spatial constraints from prior SEEG trajectories (\"Priors\") to improve safety and reduce manual adjustments, without increasing planning time.</p><p><strong>Methods: </strong>Retrospective validation based on 159 previously implanted trajectories (11 cases) planned by the clinical standard CAP and CAP constrained with spatial priors (\"CAP + Priors\"). Constraints included 31 target and 51 entry zones, created from 98 consecutive patients (763 implanted SEEG trajectories). Each of the 159 previously implanted trajectories was planned by two fellows, once with CAP and once with CAP + Priors, in a randomized order. The time taken to generate the initial computer-generated plan (T1) and the user-edited final plan (T2) were recorded together with the proportions of electrodes that required subsequent adjustments. Clinical implantability was assessed via a blinded review of each trajectory by five independent epilepsy neurosurgeons with expertise in SEEG implantation.</p><p><strong>Results: </strong>Expert raters considered 88.5% of trajectories implantable, with no difference in acceptability between CAP alone and CAP + Priors (<i>p</i> = 0.79). Median (IQR) T1 for CAP to produce complete automated implantation was 4.6 (0.85) min vs. CAP + Priors was 6.3 (2.6) min (<i>p</i> = 0.03). There was no significant difference in T2 (time to complete surgeon-edited plan): CAP median (IQR) 105 (22) min, and CAP + Priors median (IQR) 96 (68) min (<i>p</i> = 0.92). The CAP + Priors risk score was significantly lower than that for the previously actually implanted trajectories for the 11 plans analyzed (<i>p</i> = 0.004), and no different from CAP alone planning. A significant reduction was observed in manual adjustments required with CAP + Priors in the cingulate gyrus.</p><p><strong>Conclusion: </strong>Using spatial priors from previous implantations enhances SEEG CAP and increases the granularity of trajectory planning. This approach facilitates more standardized planning and allows for the incorporation of experience from multiple expert centers, decreasing the risk of the resultant trajectories and reducing the proportion of trajectories that require manual planning without significantly increasing planning time.</p>","PeriodicalId":12575,"journal":{"name":"Frontiers in Neurology","volume":"16 ","pages":"1514442"},"PeriodicalIF":2.7000,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11905814/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in Neurology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3389/fneur.2025.1514442","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Objectives: This study aims to refine computer-assisted planning (CAP) of SEEG implantations by adding spatial constraints from prior SEEG trajectories ("Priors") to improve safety and reduce manual adjustments, without increasing planning time.

Methods: Retrospective validation based on 159 previously implanted trajectories (11 cases) planned by the clinical standard CAP and CAP constrained with spatial priors ("CAP + Priors"). Constraints included 31 target and 51 entry zones, created from 98 consecutive patients (763 implanted SEEG trajectories). Each of the 159 previously implanted trajectories was planned by two fellows, once with CAP and once with CAP + Priors, in a randomized order. The time taken to generate the initial computer-generated plan (T1) and the user-edited final plan (T2) were recorded together with the proportions of electrodes that required subsequent adjustments. Clinical implantability was assessed via a blinded review of each trajectory by five independent epilepsy neurosurgeons with expertise in SEEG implantation.

Results: Expert raters considered 88.5% of trajectories implantable, with no difference in acceptability between CAP alone and CAP + Priors (p = 0.79). Median (IQR) T1 for CAP to produce complete automated implantation was 4.6 (0.85) min vs. CAP + Priors was 6.3 (2.6) min (p = 0.03). There was no significant difference in T2 (time to complete surgeon-edited plan): CAP median (IQR) 105 (22) min, and CAP + Priors median (IQR) 96 (68) min (p = 0.92). The CAP + Priors risk score was significantly lower than that for the previously actually implanted trajectories for the 11 plans analyzed (p = 0.004), and no different from CAP alone planning. A significant reduction was observed in manual adjustments required with CAP + Priors in the cingulate gyrus.

Conclusion: Using spatial priors from previous implantations enhances SEEG CAP and increases the granularity of trajectory planning. This approach facilitates more standardized planning and allows for the incorporation of experience from multiple expert centers, decreasing the risk of the resultant trajectories and reducing the proportion of trajectories that require manual planning without significantly increasing planning time.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
目的:本研究旨在改进 SEEG 植入的计算机辅助规划(CAP),方法是在不增加规划时间的情况下,增加先前 SEEG 轨迹的空间约束("Priors"),以提高安全性并减少手动调整:方法:根据临床标准 CAP 和受空间先验约束的 CAP("CAP + 先验")规划的 159 个先前植入轨迹(11 个病例)进行回顾性验证。约束包括 31 个目标区和 51 个入口区,由 98 名连续患者(763 个植入 SEEG 轨迹)创建。之前植入的 159 条轨迹中的每一条都由两名研究员按照随机顺序进行规划,一次使用 CAP,一次使用 CAP + Priors。计算机生成初始计划(T1)和用户编辑最终计划(T2)所需的时间以及需要后续调整的电极比例都被记录下来。由五位具有 SEEG 植入专业知识的独立癫痫神经外科医生对每个轨迹进行盲审,评估临床植入性:专家评审员认为 88.5% 的轨迹可植入,仅 CAP 与 CAP + Priors 之间的可接受性无差异(p = 0.79)。CAP 实现完全自动植入的 T1 中位数(IQR)为 4.6 (0.85) 分钟,而 CAP + Priors 为 6.3 (2.6) 分钟(p = 0.03)。T2(完成外科医生编辑计划的时间)无明显差异:CAP中位数(IQR)为105(22)分钟,CAP + Priors中位数(IQR)为96(68)分钟(p = 0.92)。在所分析的 11 个计划中,CAP + Priors 风险评分明显低于之前实际植入的轨迹评分(p = 0.004),与单用 CAP 计划相比没有差异。使用 CAP + Priors 时,扣带回所需的手动调整明显减少:结论:使用先前植入的空间先验增强了 SEEG CAP,并提高了轨迹规划的粒度。这种方法有助于提高规划的标准化程度,并可吸收多个专家中心的经验,从而降低由此产生的轨迹的风险,并在不显著增加规划时间的情况下减少需要手动规划的轨迹比例。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Frontiers in Neurology
Frontiers in Neurology CLINICAL NEUROLOGYNEUROSCIENCES -NEUROSCIENCES
CiteScore
4.90
自引率
8.80%
发文量
2792
审稿时长
14 weeks
期刊介绍: The section Stroke aims to quickly and accurately publish important experimental, translational and clinical studies, and reviews that contribute to the knowledge of stroke, its causes, manifestations, diagnosis, and management.
期刊最新文献
A new nomogram for predicting 90-day outcomes of intravenous thrombolysis in patients with acute ischaemic stroke. Adherence to rehabilitation exercise and influencing factors among people with acute stroke: a cross-sectional study. Assessing the impact of moxibustion on colonic mucosal integrity and gut microbiota in a rat model of cerebral ischemic stroke: insights from the "brain-gut axis" theory. Computer-assisted stereoelectroencephalography planning: center-specific priors enhance planning. Gait impairments in patients with bilateral vestibulopathy and chronic unilateral vestibulopathy.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1