A novel intradermal combination vaccine for PCV2 and Mycoplasma hyopneumoniae protection in swine: its use with Lawsonia intracellularis and PRRSV vaccines.

IF 3 2区 农林科学 Q1 VETERINARY SCIENCES Porcine Health Management Pub Date : 2025-03-13 DOI:10.1186/s40813-025-00426-9
Basav N Hangalapura, Maarten Witvliet, Antonius A C Jacobs, Ruud P A M Segers
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Abstract

The combined, intradermal application of multiple vaccines against key diseases in swine offers many benefits, including reduced time and labor costs, and improved animal welfare due to fewer injections and manipulations. This study investigated the efficacy of a newly developed intradermal combination vaccine for Porcine circovirus 2 (PCV2) and Mycoplasma hyopneumoniae (M hyo) (PCV M Hyo ID vaccine) in swine. The vaccine was evaluated for its efficacy against PCV2 and M hyo infection and its concurrent mixed use with Lawsonia intracellularis (LI) and non-mixed use with Porcine reproductive and respiratory syndrome virus (PRRSV) vaccines. The findings demonstrated that the PCV M Hyo ID combination vaccine is efficacious against PCV2 and M hyo infection. Furthermore, the new PCV M Hyo ID combination vaccine can also be administered simultaneously and at the same anatomical location after mixing with LI ID vaccine, and next to PRRS ID vaccine, to efficiently protect pigs from all four major diseases in swine. The efficacy with the combination of vaccines was equivalent to that of the single vaccines.

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来源期刊
Porcine Health Management
Porcine Health Management Veterinary-Food Animals
CiteScore
5.40
自引率
5.90%
发文量
49
审稿时长
14 weeks
期刊介绍: Porcine Health Management (PHM) is an open access peer-reviewed journal that aims to publish relevant, novel and revised information regarding all aspects of swine health medicine and production.
期刊最新文献
A novel intradermal combination vaccine for PCV2 and Mycoplasma hyopneumoniae protection in swine: its use with Lawsonia intracellularis and PRRSV vaccines. Part II: understanding pain in pigs-pain assessment in pigs with spontaneously occurring diseases or injuries. Part I: understanding pain in pigs-basic knowledge about pain assessment, measures and therapy. Cross-sectional study of Mycoplasma hyopharyngis, Mycoplasma hyopneumoniae, Mycoplasma hyorhinis and Mycoplasma hyosynoviae in the tonsils of fattening pigs from Central-Eastern Europe. Experimental efficacy of vaccination of weaned piglets with a modified-live commercial PRRS virus vaccine against the challenge with a Spanish highly virulent PRRSV-1 strain.
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