Recent Neuropathology Concepts.

IF 1.8 4区 医学 Q3 PATHOLOGY Toxicologic Pathology Pub Date : 2025-06-01 Epub Date: 2025-03-13 DOI:10.1177/01926233251320056
Pierre Maliver, Julie Boisclair, Ingrid Pardo, Luisa Bell, Kerstin Hahn, Benedek Pesti, Stefanie Arms, Elizabeth Galbreath
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Abstract

The last session of the 2024 European Society of Toxicologic Pathology Congress was dedicated to recent neuro concepts, encompassing various topics including artificial intelligence (AI) applied to toxicologic pathology, new technologies for visualization and/or analysis of tissues, as well as specific case reports. Four presentations detailed the role of AI and computational pathology for toxicologic pathologists, usage of cryofluorescent tomography in neuropathology, blood-brain barrier organoids in early drug screening, and spatial transcriptomics in toxicologic pathology. In addition, there were two short presentations about a spontaneous brain lesion in Beagle dogs as well as central nervous system lesions related to adeno-associated virus vectors administration in various preclinical species. This session underscored the current and prospective impact of emerging technologies on drug screening and development.

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近期神经病理学概念。
2024年欧洲毒理学病理学学会大会的最后一届会议致力于最近的神经概念,涵盖各种主题,包括应用于毒理学病理学的人工智能(AI),组织可视化和/或分析的新技术,以及具体病例报告。四篇报告详细介绍了人工智能和计算病理学在毒理学病理学家中的作用、冷冻荧光断层扫描在神经病理学中的应用、血脑屏障类器官在早期药物筛选中的应用以及空间转录组学在毒理学病理学中的应用。此外,还有两个关于Beagle犬自发性脑损伤的简短报告,以及与各种临床前物种中腺相关病毒载体管理相关的中枢神经系统损伤。本次会议强调了新兴技术对药物筛选和开发的当前和未来影响。
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来源期刊
Toxicologic Pathology
Toxicologic Pathology 医学-病理学
CiteScore
4.70
自引率
20.00%
发文量
57
审稿时长
6-12 weeks
期刊介绍: Toxicologic Pathology is dedicated to the promotion of human, animal, and environmental health through the dissemination of knowledge, techniques, and guidelines to enhance the understanding and practice of toxicologic pathology. Toxicologic Pathology, the official journal of the Society of Toxicologic Pathology, will publish Original Research Articles, Symposium Articles, Review Articles, Meeting Reports, New Techniques, and Position Papers that are relevant to toxicologic pathology.
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