Evaluation of the bone-enhancing potential of calcium phosphate coatings with different morphologies on titanium surfaces under oxidative stress conditions
Keyuan Xu , Jia Chen , Hongyu Luo , Shuangyun Liu , Shaobo Ni , Xinkun Shen , Yilong Dong , Xiaoyi Pan
{"title":"Evaluation of the bone-enhancing potential of calcium phosphate coatings with different morphologies on titanium surfaces under oxidative stress conditions","authors":"Keyuan Xu , Jia Chen , Hongyu Luo , Shuangyun Liu , Shaobo Ni , Xinkun Shen , Yilong Dong , Xiaoyi Pan","doi":"10.1016/j.matchemphys.2025.130703","DOIUrl":null,"url":null,"abstract":"<div><div>Calcium phosphate (CaP) coatings with varying morphologies were applied to the surface of titanium using an immersion method, and their anti-inflammatory and bone-enhancing properties were examined under oxidative stress (OS) conditions. The experimental results demonstrated that hydroxyapatite-treated titanium exhibits superior antioxidant capabilities compared to pure titanium. This improvement supports cell attachment, growth, and osteogenic differentiation of MC3T3-E1 cells by efficiently modulating the bone immune microenvironment. Meanwhile, the CaP coatings formed under different pH conditions show significant differences, with Ti–HAs demonstrating superior performance compared to Ti-HAp, especially under OS conditions.</div></div>","PeriodicalId":18227,"journal":{"name":"Materials Chemistry and Physics","volume":"339 ","pages":"Article 130703"},"PeriodicalIF":4.3000,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Materials Chemistry and Physics","FirstCategoryId":"88","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0254058425003499","RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Calcium phosphate (CaP) coatings with varying morphologies were applied to the surface of titanium using an immersion method, and their anti-inflammatory and bone-enhancing properties were examined under oxidative stress (OS) conditions. The experimental results demonstrated that hydroxyapatite-treated titanium exhibits superior antioxidant capabilities compared to pure titanium. This improvement supports cell attachment, growth, and osteogenic differentiation of MC3T3-E1 cells by efficiently modulating the bone immune microenvironment. Meanwhile, the CaP coatings formed under different pH conditions show significant differences, with Ti–HAs demonstrating superior performance compared to Ti-HAp, especially under OS conditions.
期刊介绍：
Materials Chemistry and Physics is devoted to short communications, full-length research papers and feature articles on interrelationships among structure, properties, processing and performance of materials. The Editors welcome manuscripts on thin films, surface and interface science, materials degradation and reliability, metallurgy, semiconductors and optoelectronic materials, fine ceramics, magnetics, superconductors, specialty polymers, nano-materials and composite materials.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
