Oliver Hermann , Carla Leonardi , Karin Petrini , Elizabeth Coulthard , George Stothart
{"title":"Measuring implicit line orientation discrimination using fast periodic visual stimulation","authors":"Oliver Hermann , Carla Leonardi , Karin Petrini , Elizabeth Coulthard , George Stothart","doi":"10.1016/j.neuropsychologia.2025.109122","DOIUrl":null,"url":null,"abstract":"<div><div>The fast periodic visual stimulation oddball paradigm (FPVS-oddball) is an electroencephalography (EEG) marker of discrimination between two classes of frequency tagged stimuli (standards and oddballs). Here, we probe low-level visual function using FPVS-oddball, with a view to its future use as a sensitive diagnostic marker of visuoperceptual cognitive impairment. Thirty participants (21 (±5) years, 7 males) completed five FPVS-oddball conditions that implicitly measured their ability to discriminate an oddball line orientation (1°,5°,10°,30°,80°), from a standard vertical line, as well as an equiprobable control condition. Twenty-four participants (24 (±5) years, 5 males) completed a retest session around one month later. Following 100s of recording, activity at the oddball presentation frequency, a neural signal of discrimination between standard and oddball stimuli, was observed in response to lines of 5° and above. The magnitude of this oddball response increased as oddball lines deviated more from vertical. Demonstrating consistency in individual participants, oddball responses were present in 30/30 participants in response to a deviation of 30° and 29/30 in response to a deviation of 80°. At larger deviations, oddball responses were highly reliable between sessions, measured using intraclass correlations. Overall, this study showed that FPVS-oddball can consistently and reliably measure line orientation discrimination in individual participants. The consistency and reliability of oddball responses in the cognitively healthy, could provide a strong baseline that clinical group's performance could be compared to, guiding neurocognitive assessment.</div></div>","PeriodicalId":19279,"journal":{"name":"Neuropsychologia","volume":"211 ","pages":"Article 109122"},"PeriodicalIF":2.0000,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neuropsychologia","FirstCategoryId":"102","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0028393225000570","RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BEHAVIORAL SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
The fast periodic visual stimulation oddball paradigm (FPVS-oddball) is an electroencephalography (EEG) marker of discrimination between two classes of frequency tagged stimuli (standards and oddballs). Here, we probe low-level visual function using FPVS-oddball, with a view to its future use as a sensitive diagnostic marker of visuoperceptual cognitive impairment. Thirty participants (21 (±5) years, 7 males) completed five FPVS-oddball conditions that implicitly measured their ability to discriminate an oddball line orientation (1°,5°,10°,30°,80°), from a standard vertical line, as well as an equiprobable control condition. Twenty-four participants (24 (±5) years, 5 males) completed a retest session around one month later. Following 100s of recording, activity at the oddball presentation frequency, a neural signal of discrimination between standard and oddball stimuli, was observed in response to lines of 5° and above. The magnitude of this oddball response increased as oddball lines deviated more from vertical. Demonstrating consistency in individual participants, oddball responses were present in 30/30 participants in response to a deviation of 30° and 29/30 in response to a deviation of 80°. At larger deviations, oddball responses were highly reliable between sessions, measured using intraclass correlations. Overall, this study showed that FPVS-oddball can consistently and reliably measure line orientation discrimination in individual participants. The consistency and reliability of oddball responses in the cognitively healthy, could provide a strong baseline that clinical group's performance could be compared to, guiding neurocognitive assessment.
期刊介绍:
Neuropsychologia is an international interdisciplinary journal devoted to experimental and theoretical contributions that advance understanding of human cognition and behavior from a neuroscience perspective. The journal will consider for publication studies that link brain function with cognitive processes, including attention and awareness, action and motor control, executive functions and cognitive control, memory, language, and emotion and social cognition.