Five-year follow-up of a randomized weight loss trial on a digital health behaviour change support system

IF 3.8 2区 医学 Q1 ENDOCRINOLOGY & METABOLISM International Journal of Obesity Pub Date : 2025-03-15 DOI:10.1038/s41366-025-01742-4
Eero Turkkila, Taru Pekkala, Heta Merikallio, Marko Merikukka, Laura Heikkilä, Janne Hukkanen, Harri Oinas-Kukkonen, Tuire Salonurmi, Anna-Maria Teeriniemi, Terhi Jokelainen, Markku J. Savolainen
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Abstract

The weight regain after successful weight loss is a common challenge. This study aimed to assess the long-term effectiveness of a web-based health behaviour change support system (HBCSS) utilizing persuasive systems design (PSD) and methods of cognitive behavioural therapy (CBT). We have previously demonstrated the two-year effectiveness of the HBCSS. In total, 532 participants with overweight or obesity (BMI 27–35 kg m−2) were split into three groups with different intensities of intervention: CBT-based group counselling, self-help guidance (SHG), and usual care. These groups were further divided into HBCSS and non-HBCSS groups. The HBCSS was a 52-week programme. The follow-up took five years in total. Mean weight change (%) (95% CI) from baseline among HBCSS and non-HBCSS users was 1.5 (−0.02 to 2.9), p = 0.056 and 1.9 (0.3–3.3), p = 0.005, respectively, at five years. Of the six groups, the SHG group without HBCSS had a statistically significant increase in weight (%) from baseline at five years (3.1, 95% CI 0.6 to 5.6, p = 0.010). The other groups did not have a significant increase in weight. There was no significant difference between groups at five years in weight. Fewer blood pressure medications were started over the five-year period in HBCSS group (p = 0.046). The 12-month HBCSS intervention was not able to maintain reduced weight better than non-HBCSS at 5 years. However, there were significant weight difference favouring HBCSS over the whole 5-year period. The decrease in the need for antihypertensives suggests that the significant weight loss by HBCSS at early years has a health-promoting legacy effect.

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一项基于数字健康行为改变支持系统的随机减肥试验的五年随访。
背景:减肥成功后体重反弹是一个常见的挑战。本研究旨在评估基于网络的健康行为改变支持系统(HBCSS)的长期有效性,该系统采用说服系统设计(PSD)和认知行为治疗(CBT)方法。我们之前已经证明了HBCSS的两年有效性。方法:将532名体重超重或肥胖(BMI 27-35 kg m-2)的参与者分为三组,采用不同强度的干预:基于cbt的小组咨询、自助指导(SHG)和常规护理。这些组进一步分为HBCSS组和非HBCSS组。HBCSS是一个52周的项目。随访总共花了5年时间。结果:五年内,HBCSS和非HBCSS使用者的平均体重变化(%)(95% CI)与基线相比分别为1.5(-0.02至2.9),p = 0.056和1.9 (0.3-3.3),p = 0.005。在六组中,无HBCSS的SHG组在五年时的体重(%)较基线有统计学意义的增加(3.1,95% CI 0.6 ~ 5.6, p = 0.010)。其他组的体重没有明显增加。五岁时,各组之间的体重没有显著差异。5年期间,HBCSS组开始使用降压药物的人数较少(p = 0.046)。结论:12个月的HBCSS干预在5年时不能比非HBCSS更好地维持体重。然而,在整个5年期间,有显著的体重差异有利于HBCSS。抗高血压药物需求的减少表明,早期HBCSS的显著体重减轻具有促进健康的遗留效应。
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来源期刊
International Journal of Obesity
International Journal of Obesity 医学-内分泌学与代谢
CiteScore
10.00
自引率
2.00%
发文量
221
审稿时长
3 months
期刊介绍: The International Journal of Obesity is a multi-disciplinary forum for research describing basic, clinical and applied studies in biochemistry, physiology, genetics and nutrition, molecular, metabolic, psychological and epidemiological aspects of obesity and related disorders. We publish a range of content types including original research articles, technical reports, reviews, correspondence and brief communications that elaborate on significant advances in the field and cover topical issues.
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