Managing Cardiogenic Shock Caused by Acute Myocardial Infarction: Invisible Challenges Revealed in a Statewide Registry

IF 21.7 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Journal of the American College of Cardiology Pub Date : 2025-03-17 DOI:10.1016/j.jacc.2025.02.027
Eric P. Cantey, Aaron Lopacinski, Milan Seth, David E. Hamilton, Elias J. Dayoub, Siddharth Gandhi, Mir B. Basir, Amir Kaki, Ryan D. Madder, Devraj Sukul, Hitinder S. Gurm
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Abstract

Section snippets

Methods

The BMC2 registry is a quality improvement initiative of all nonfederal hospitals that perform percutaneous coronary intervention (PCI) in Michigan.3 Prospective patient-level data are collected through the NCDR (National Cardiovascular Data Registry) CathPCI system. Novel variables are also collected to drive statewide quality improvement.

Results

Of 24,744 primary PCIs for STEMI, 2,392 (9.7%) were complicated by AMI-CS. Of these, 927 (38.8%) were excluded primarily due to persistent neurologic deficit after cardiac arrest (n = 909; 38.0%). Among the remaining 1,465 patients, 724 (49.4%) were treated without MCS, 355 (24.2%) with IABP, 364 (24.9%) with mAFP, and 22 (1.5%) with other MCS (n = 14 for extracorporeal membrane oxygenation). Figure 1 shows annualized AMI-CS case volume and MCS utilization patterns by site. Each site treated a

Discussion

In a contemporary cohort of patients with AMI-CS with similar inclusion and exclusion criteria as the DanGer Shock trial: 1) there was low annual AMI-CS prevalence per site; 2) there was heterogeneous utilization of MCS for the treatment of AMI-CS; and 3) there was low utilization of intraprocedural RHC in AMI-CS.

Conclusions

AMI-CS is uncommonly encountered by most hospitals, resulting in limited experience with the use of mAFP. Successful translation of the DanGer Shock trial to contemporary care will require the implementation of shock protocols and hub and spoke partnerships to optimize the care and management of AMI-CS patients.

Funding Support and Author Disclosures

Support for BMC2 is provided by Blue Cross Blue Shield of Michigan (BCBSM) and Blue Care Network as part of the BCBSM Value Partnerships program. Although BCBSM and BMC2 work collaboratively, the opinions, beliefs and viewpoints expressed by the authors do not necessarily reflect the opinions, beliefs, and viewpoints of BCBSM or any of its employees. Further, BCBSM does not have access to BMC2 data, and all patient episodes occurring at engaged hospitals are included in the data registries,
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CiteScore
42.70
自引率
3.30%
发文量
5097
审稿时长
2-4 weeks
期刊介绍: The Journal of the American College of Cardiology (JACC) publishes peer-reviewed articles highlighting all aspects of cardiovascular disease, including original clinical studies, experimental investigations with clear clinical relevance, state-of-the-art papers and viewpoints. Content Profile: -Original Investigations -JACC State-of-the-Art Reviews -JACC Review Topics of the Week -Guidelines & Clinical Documents -JACC Guideline Comparisons -JACC Scientific Expert Panels -Cardiovascular Medicine & Society -Editorial Comments (accompanying every Original Investigation) -Research Letters -Fellows-in-Training/Early Career Professional Pages -Editor’s Pages from the Editor-in-Chief or other invited thought leaders
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Correction Contents Managing Cardiogenic Shock Caused by Acute Myocardial Infarction: Invisible Challenges Revealed in a Statewide Registry Biomarker-Based Stroke Risk Assessment in Atrial Fibrillation A New Era in Electrophysiology
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