Diverse Applications of DNA Origami as a Cross-disciplinary Tool

Abstract

As knowledge from a single discipline is no longer sufficient to keep pace with the growing complexity of technological advancements, interdisciplinary collaboration has become a crucial driver of innovation. DNA nanotechnology exemplifies this integration, serving as a field where cross-disciplinary communication is particularly prominent. Since its introduction by Rothemund in 2006, DNA origami has proven to be a powerful tool for interdisciplinary research, offering exceptional structural stability, programmability, and addressability. This review provides an overview of the development of DNA origami technology, highlights its major advances, and explores its innovative applications across various disciplines in recent years, showcasing its vast potential and future prospects. We believe DNA origami is poised for even broader applications, driving progress across multiple fields.