Aptamer-Directed Bidirectional Modulation of Vascular Niches for Promoted Regeneration of Segmental Trachea Defect (Adv. Funct. Mater. 12/2025)

IF 19 1区 材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY Advanced Functional Materials Pub Date : 2025-03-18 DOI:10.1002/adfm.202570068
Runfeng Cao, Zhenying Chen, Qing Ye, Weiyan Sun, Weikang Lin, Hai Tang, Xingseng Yang, Junhao Liang, Yi Chen, Lei Wang, Qingfeng Bai, Ziying Pan, Yulong Hu, Dong Xie, Deping Zhao, Yong Hu, Chang Chen
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Abstract

Tissue-Specific Aptamer Matrices

In article number 2409071, Dong Xie, Deping Zhao, Yong Hu, Chang Chen, and co-workers successfully engineer a biomimetic trachea with regenerated vascular connective tissue scattered between avascular cartilage rings using the assembly of two distinct tissue-specific aptamer matrices. This approach fosters the development of (a)vascular niches in reconstructed trachea after end-to-end anastomosis, along with optimal structural, mechanical, and physiological features.

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色聚体定向双向调节血管壁龛以促进气管节段性缺损的再生(Adv. Funct. Mater.)
文章编号:2409071,谢东,赵德平,胡勇,陈畅等人利用两种不同的组织特异性适配体基质的组装,成功地构建了一个由分散在无血管软骨环之间的血管结缔组织再生的仿生气管。这种方法促进了(a)端到端吻合后重建气管血管壁龛的发育,并具有最佳的结构、机械和生理特征。
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来源期刊
Advanced Functional Materials
Advanced Functional Materials 工程技术-材料科学:综合
CiteScore
29.50
自引率
4.20%
发文量
2086
审稿时长
2.1 months
期刊介绍: Firmly established as a top-tier materials science journal, Advanced Functional Materials reports breakthrough research in all aspects of materials science, including nanotechnology, chemistry, physics, and biology every week. Advanced Functional Materials is known for its rapid and fair peer review, quality content, and high impact, making it the first choice of the international materials science community.
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