Correlating Migrainous Features With Vestibular-Evoked Myogenic Potentials in Vestibular Migraine.

IF 1.7 4区医学 Q2 OTORHINOLARYNGOLOGY Clinical Otolaryngology Pub Date : 2025-03-16 DOI:10.1111/coa.14298

Yun-Chen Huang, Yi-Ho Young

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Abstract

Objective: This study aimed to find biomarkers for assessing migrainous features, that is, migrainous headache, sensitivity to sound and light (phono- and photophobia) and visual aura in vestibular migraine (VM) patients.

Design: A retrospective cohort study.

Setting: University hospital.

Participants: A total of 400 definitive VM patients were classified into four groups based on the number of migrainous features. Group A (n = 45) had one migrainous feature (migrainous headache). Group B (n = 70) had migrainous headache along with phono- and photophobia, while Group C (n = 55) had migrainous headache and visual aura. Those with all three migrainous features were categorised in Group D (n = 230). Another 40 healthy subjects were also enrolled for comparison.

Main outcomes measure: All subjects underwent an inner ear test battery comprising audiometry, cervical, ocular vestibular-evoked myogenic potential (cVEMP, oVEMP) and caloric tests.

Results: Significant difference in mean age was observed in Group A when compared to Groups B-D, indicating that younger age might not be associated with the manifestation of all three migrainous features. No significant difference was observed among the four groups irrespective of gender and inner ear test battery. Via multivariate logistic regression, the oVEMP test (adjusted odds ratio, aOR = 2.60) was superior to the cVEMP test as a stronger indicator for the presence of phono- and photophobia. Conversely, the cVEMP test (aOR = 2.59) served as a stronger indicator for the presence of visual aura than the oVEMP test.

Conclusion: The oVEMP test may act as a biomarker for phono- and photophobia, whereas the cVEMP test shows a strong capacity to predict visual aura.

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来源期刊

Clinical Otolaryngology 医学-耳鼻喉科学

CiteScore

4.00

自引率

4.80%

发文量

106

审稿时长

>12 weeks

期刊介绍： Clinical Otolaryngology is a bimonthly journal devoted to clinically-oriented research papers of the highest scientific standards dealing with: current otorhinolaryngological practice audiology, otology, balance, rhinology, larynx, voice and paediatric ORL head and neck oncology head and neck plastic and reconstructive surgery continuing medical education and ORL training The emphasis is on high quality new work in the clinical field and on fresh, original research. Each issue begins with an editorial expressing the personal opinions of an individual with a particular knowledge of a chosen subject. The main body of each issue is then devoted to original papers carrying important results for those working in the field. In addition, topical review articles are published discussing a particular subject in depth, including not only the opinions of the author but also any controversies surrounding the subject. • Negative/null results In order for research to advance, negative results, which often make a valuable contribution to the field, should be published. However, articles containing negative or null results are frequently not considered for publication or rejected by journals. We welcome papers of this kind, where appropriate and valid power calculations are included that give confidence that a negative result can be relied upon.