{"title":"Age-related changes in depression symptom networks in children in China with parental absence: A comparative analysis of youth aged nine to 18.","authors":"Qian-Nan Ruan, Cheng-Han Li, Su Xu, Wen-Jing Yan","doi":"10.1016/j.jad.2025.03.082","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>The network perspective on psychopathology views depression as a system of interacting symptoms. Research shows that mental health problems change with age. Children with parental absence are at risk for depression, but it's unclear how their depressive symptom networks evolve across developmental stages.</p><p><strong>Method: </strong>Network analysis was conducted on data from 179,519 children with parental absence who completed the depression scale CESD. The Graphical LASSO algorithm was used to construct depressive symptom networks for each age group. Global network metrics and centrality measures were then calculated and compared across age groups.</p><p><strong>Results: </strong>Depressive symptoms increased with age, with mean CES-D scores rising from 3.44 at age nine to 10.8 at age 17. Network density showed a general increase from age nine (0.045) to age 17 (0.047), while average path length decreased from age nine (18.380) to age 18 (15.338) and clustering coefficient decreased from age 9 (0.879) to age 18 (0.706). Closeness centrality demonstrated the most substantial age-related effect (F = 1445.111, p < 0.001, η<sup>2</sup> = 0.225), with significant increases from early to late adolescence. Core emotional symptoms remained central across ages, while loneliness and feelings of failure became more central with age.</p><p><strong>Conclusion: </strong>As children with parental absence age, their depressive symptom networks become more severe, interconnected, and efficiently structured. This suggests a need for age-specific interventions addressing both core symptoms and emerging adolescent self-evaluative concerns, advancing our understanding of developmental psychopathology in this vulnerable group.</p>","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":" ","pages":""},"PeriodicalIF":4.9000,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of affective disorders","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.jad.2025.03.082","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Background: The network perspective on psychopathology views depression as a system of interacting symptoms. Research shows that mental health problems change with age. Children with parental absence are at risk for depression, but it's unclear how their depressive symptom networks evolve across developmental stages.
Method: Network analysis was conducted on data from 179,519 children with parental absence who completed the depression scale CESD. The Graphical LASSO algorithm was used to construct depressive symptom networks for each age group. Global network metrics and centrality measures were then calculated and compared across age groups.
Results: Depressive symptoms increased with age, with mean CES-D scores rising from 3.44 at age nine to 10.8 at age 17. Network density showed a general increase from age nine (0.045) to age 17 (0.047), while average path length decreased from age nine (18.380) to age 18 (15.338) and clustering coefficient decreased from age 9 (0.879) to age 18 (0.706). Closeness centrality demonstrated the most substantial age-related effect (F = 1445.111, p < 0.001, η2 = 0.225), with significant increases from early to late adolescence. Core emotional symptoms remained central across ages, while loneliness and feelings of failure became more central with age.
Conclusion: As children with parental absence age, their depressive symptom networks become more severe, interconnected, and efficiently structured. This suggests a need for age-specific interventions addressing both core symptoms and emerging adolescent self-evaluative concerns, advancing our understanding of developmental psychopathology in this vulnerable group.
期刊介绍:
The Journal of Affective Disorders publishes papers concerned with affective disorders in the widest sense: depression, mania, mood spectrum, emotions and personality, anxiety and stress. It is interdisciplinary and aims to bring together different approaches for a diverse readership. Top quality papers will be accepted dealing with any aspect of affective disorders, including neuroimaging, cognitive neurosciences, genetics, molecular biology, experimental and clinical neurosciences, pharmacology, neuroimmunoendocrinology, intervention and treatment trials.