MLDAN:Multi-scale large kernel decomposition attention network for super-resolution of lung computed tomography images

IF 4.9 2区 医学 Q1 ENGINEERING, BIOMEDICAL Biomedical Signal Processing and Control Pub Date : 2025-09-01 Epub Date: 2025-03-19 DOI:10.1016/j.bspc.2025.107795
Yanmei Li , Xiaoshuang Li , Jian Luo , Tao Yu , Jingshi Deng , Qibin Yang
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Abstract

Computed Tomography(CT) is widely used in medical diagnostics, with high-resolution(HR) CT images providing essential details for disease diagnosis. However, factors like equipment limitations and motion artifacts can result in low-resolution(LR) CT images. To address this, researchers have explored image super-resolution(SR) techniques to restore HR images, but challenges remain, particularly with lung CT images. One key challenge is the diversity of lung structures, such as variations in the shape and size of the lung parenchyma, bronchi, blood vessels, and lesions, which standard convolutional neural networks(CNNs) struggle to recover. In this paper, a method based on multi-scale large kernel decomposition attention network(MLDAN) for lung CT image super-resolution is proposed. This method captures detailed features of lung structures through multi-scale large kernel decomposition attention(MLDA) mechanism. To further enhance irregular lung edge details, we designed an anatomy-aware dynamic fusion module(ADFM), which adapts to complex lung features using deformable convolutions. Additionally, preserving global information between lung structures and their surrounding tissues is crucial for disease diagnosis. To maintain this, we incorporated MLDA as a Token Mixer within the MetaFormer architecture to efficiently model global dependencies. Experimental results on the public COVID-CT dataset and the lung cancer dataset IQ-OTH/NCCD show that the proposed method outperforms state-of-the-art(SOTA) techniques in both objective metrics(PSNR/SSIM) and visual quality, while maintaining a reduced parameter count. This method has significant potential for application and provides support for the early diagnosis of lung diseases. Codes are available at https://github.com/tiantianbaipiao/MLDAN

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基于多尺度大核分解的肺计算机断层图像超分辨率关注网络
计算机断层扫描(CT)广泛应用于医学诊断,其高分辨率(HR) CT图像为疾病诊断提供了必要的细节。然而,设备限制和运动伪影等因素可能导致低分辨率(LR) CT图像。为了解决这个问题,研究人员已经探索了图像超分辨率(SR)技术来恢复HR图像,但挑战仍然存在,特别是肺部CT图像。一个关键的挑战是肺结构的多样性,如肺实质、支气管、血管和病变的形状和大小的变化,标准卷积神经网络(cnn)难以恢复。本文提出了一种基于多尺度大核分解注意网络(MLDAN)的肺CT图像超分辨方法。该方法通过多尺度大核分解注意(MLDA)机制捕获肺结构的详细特征。为了进一步增强不规则肺边缘的细节,我们设计了一个解剖学感知的动态融合模块(ADFM),该模块使用可变形的卷积来适应复杂的肺特征。此外,保存肺结构及其周围组织之间的全局信息对于疾病诊断至关重要。为了维护这一点,我们将MLDA作为Token Mixer合并到MetaFormer体系结构中,以有效地建模全局依赖关系。在公开的COVID-CT数据集和肺癌数据集IQ-OTH/NCCD上的实验结果表明,该方法在保持较少参数计数的同时,在客观指标(PSNR/SSIM)和视觉质量方面都优于最先进的(SOTA)技术。该方法具有重要的应用潜力,为肺部疾病的早期诊断提供支持。代码可在https://github.com/tiantianbaipiao/MLDAN上获得
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来源期刊
Biomedical Signal Processing and Control
Biomedical Signal Processing and Control 工程技术-工程:生物医学
CiteScore
9.80
自引率
13.70%
发文量
822
审稿时长
4 months
期刊介绍: Biomedical Signal Processing and Control aims to provide a cross-disciplinary international forum for the interchange of information on research in the measurement and analysis of signals and images in clinical medicine and the biological sciences. Emphasis is placed on contributions dealing with the practical, applications-led research on the use of methods and devices in clinical diagnosis, patient monitoring and management. Biomedical Signal Processing and Control reflects the main areas in which these methods are being used and developed at the interface of both engineering and clinical science. The scope of the journal is defined to include relevant review papers, technical notes, short communications and letters. Tutorial papers and special issues will also be published.
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