Diagnosis of Acute-on-Chronic Liver Failure in Critically Ill Patients With Cirrhosis Using Administrative Data.

IF 7.6 1区 医学 Q1 GASTROENTEROLOGY & HEPATOLOGY American Journal of Gastroenterology Pub Date : 2025-10-01 Epub Date: 2025-03-17 DOI:10.14309/ajg.0000000000003422
Luis Garrido-Trevino, Soongjin Ahn, Elliot B Tapper, Olivia C Walker, Gerald Ogola, Sumeet K Asrani
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Abstract

Introduction: We evaluated the positive predictive value (PPV) of International Classification of Diseases, Tenth Revision ( ICD-10 ) codes used to identify organ failures in critically ill patients with cirrhosis.

Methods: A cohort of 315 hospitalized cirrhosis patients was analyzed. PPVs were calculated using chart review as the reference standard.

Results: Three hundred four patients had an ICD-10 code for cirrhosis. The PPV for liver failure was 33.0%, kidney failure 71.4%, respiratory failure 79.9%, circulatory failure 84.0%, and brain failure 33.3%. Adding laboratory thresholds increased PPVs.

Discussion: ICD-10 codes accurately identify organ failures in critically ill patients with cirrhosis and may be helpful for identifying cases of acute-on-chronic liver failure within administrative data.

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应用行政资料诊断肝硬化危重患者急慢性肝功能衰竭。
目的:我们评估ICD-10代码用于识别肝硬化危重患者器官衰竭的阳性预测值(PPV)。方法:对315例肝硬化住院患者进行队列分析。以图表回顾作为参考标准计算ppv。结果:304例患者的ICD-10编码为肝硬化。肝衰竭的PPV为33.0%,肾功能衰竭为71.4%,呼吸衰竭为79.9%,循环衰竭为84.0%,脑衰竭为33.3%。增加实验室阈值会增加ppv。结论:ICD-10代码准确识别肝硬化危重患者的器官衰竭,并可能有助于在行政数据中识别ACLF病例。
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来源期刊
American Journal of Gastroenterology
American Journal of Gastroenterology 医学-胃肠肝病学
CiteScore
11.40
自引率
5.10%
发文量
458
审稿时长
12 months
期刊介绍: Published on behalf of the American College of Gastroenterology (ACG), The American Journal of Gastroenterology (AJG) stands as the foremost clinical journal in the fields of gastroenterology and hepatology. AJG offers practical and professional support to clinicians addressing the most prevalent gastroenterological disorders in patients.
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