Cutting-edge insights: line-field confocal optical coherence tomography and 5% cyclosporine for early lichen sclerosus treatment.

IF 1.3 Q2 DERMATOLOGY Dermatology Reports Pub Date : 2025-11-05 Epub Date: 2025-03-18 DOI:10.4081/dr.2025.10279
Caterina Mariarosaria Giorgio, Vittorio Tancredi, Gaetano Licata, Elvira Moscarella, Giuseppe Argenziano, Elisabetta Fulgione, Graziella Babino, Paolino Franzese, Eugenia Veronica Di Brizzi
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Abstract

Dear Editor, Atrophic lichen sclerosus (ALS) is a chronic inflammatory dermatosis with significant morbidity, primarily affecting the genital area. The disease is often misdiagnosed or underdiagnosed, resulting in delayed treatment and progression to atrophic stages and permanent scars. While corticosteroids remain the first-line treatment, their long-term use may lead to adverse effects such as skin atrophy, prompting the need for alternative therapies. [...].

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前沿见解:LC-OCT和5%环孢素用于早期地衣硬化治疗。
萎缩性地衣硬化症(ALS)是一种慢性炎症性皮肤病,发病率高,主要影响生殖器区域。这种疾病经常被误诊或漏诊,导致治疗延迟和进展到萎缩性阶段和永久性疤痕。虽然皮质类固醇仍是一线治疗方法,但长期使用可能导致皮肤萎缩等不良反应,这促使人们需要替代疗法。环孢素(Cyclosporine)是一种钙调磷酸酶抑制剂,已显示出治疗免疫介导的皮肤病的疗效,并可通过Pentravan®载体有效递送。[…]。
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来源期刊
Dermatology Reports
Dermatology Reports DERMATOLOGY-
CiteScore
1.40
自引率
0.00%
发文量
74
审稿时长
10 weeks
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