Cutting-Edge Advancements in the Antibiotics-Gut Microbiota-Urinary Tumour Axis

IF 5.6 1区 生物学 Q2 CELL BIOLOGY Cell Proliferation Pub Date : 2025-03-17 DOI:10.1111/cpr.70023
Jie Wang, Dengxiong Li, Ruicheng Wu, Dechao Feng
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Abstract

Gut microbiota regulates urological tumors. Antibiotics induce dysbiosis, altering tumor progression/therapy: reducing carcinogen metabolism but impairing immunity. Specific bacteria enhance immune responses and combat endocrine resistance. Future research should unravel microbiota-cancer links and develop microbiome-targeted therapies to optimize outcomes while preserving diversity.

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抗生素-肠道微生物-泌尿肿瘤轴的前沿进展。
肠道微生物群调节泌尿系统肿瘤。抗生素诱导生态失调,改变肿瘤进展/治疗:减少致癌物代谢,但损害免疫力。特定细菌增强免疫反应,对抗内分泌阻力。未来的研究应该揭示微生物与癌症之间的联系,并开发针对微生物组的治疗方法,以优化结果,同时保持多样性。
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来源期刊
Cell Proliferation
Cell Proliferation 生物-细胞生物学
CiteScore
14.80
自引率
2.40%
发文量
198
审稿时长
1 months
期刊介绍: Cell Proliferation Focus: Devoted to studies into all aspects of cell proliferation and differentiation. Covers normal and abnormal states. Explores control systems and mechanisms at various levels: inter- and intracellular, molecular, and genetic. Investigates modification by and interactions with chemical and physical agents. Includes mathematical modeling and the development of new techniques. Publication Content: Original research papers Invited review articles Book reviews Letters commenting on previously published papers and/or topics of general interest By organizing the information in this manner, readers can quickly grasp the scope, focus, and publication content of Cell Proliferation.
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