Allograft bone banking experience in Nigeria: a review of first 2 years.

IF 1 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pan African Medical Journal Pub Date : 2024-12-02 eCollection Date: 2024-01-01 DOI:10.11604/pamj.2024.49.105.41103
Kehinde Adesola Alatishe, Oluwaseyi Kayode Idowu, Mustapha Alimi
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Abstract

Bone allografts are increasingly being used in various orthopaedic surgeries all over the world but were not readily available in Nigeria until year 2020 when the first bone bank facility was established at our hospital. The paper aimed to share our experience and the challenges faced within the first 2 years of operating the first bone bank in Nigeria. We retrospectively reviewed our experience between 1st September 2020 and 31st August 2022. The donors were selected based on American Association of Tissue Bank (AATB) guidelines and Nigerian National Blood Transfusion policy. Our preference was the use of allograft without late donor testing for HIV seroconversion. However, the allografts were treated, irradiated at 25 kGy, and stored in a freezer at -80°C. A total of 88 bone grafts were retrieved, processed and stored in the bone bank over the 2-year period. All allografts were from living donors. Of these, 55 (62.5%) bones were retrieved from female donors and 33 (37.5%) from males. The mean age of all donors was 55.9±15.34 years (range: 32-90 years). Bone grafts issued out from the bank were 28/88 (31.8%) in all. There was no single case of clinical infection reported. The challenges observed were limited long bone allografts, low patronage among surgeons, lack of institution preparedness to process bones from fresh dead donors and disinterest from some surgeons. Running of the first bone bank facility in Nigeria has been successful thus far. The challenges can be surmounted by creating awareness amongst the populace and surgeons of the availability and safety of bone allografts.

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尼日利亚同种异体骨库的经验:前2年的回顾。
同种异体骨移植越来越多地用于世界各地的各种骨科手术,但直到2020年在我们医院建立了第一个骨库设施后,尼日利亚才容易获得。本文旨在分享我们在尼日利亚运营第一个骨库的头两年所面临的经验和挑战。我们回顾了2020年9月1日至2022年8月31日期间的经历。献血者是根据美国组织库协会(AATB)的指导方针和尼日利亚国家输血政策选择的。我们倾向于使用同种异体移植物而不进行晚期供体HIV血清转化检测。然而,同种异体移植物经过处理,以25 kGy照射,并在-80°C冷冻保存。在2年的时间里,共回收、处理和保存了88块骨移植。所有同种异体移植物均来自活体供体。其中,55块(62.5%)骨来自女性供者,33块(37.5%)来自男性供者。献血者平均年龄55.9±15.34岁(范围32 ~ 90岁)。骨库骨移植共28/88例(31.8%)。无一例临床感染报告。所观察到的挑战是长异体骨移植有限,外科医生的赞助率低,缺乏机构准备处理新鲜死亡供者的骨骼,以及一些外科医生不感兴趣。迄今为止,尼日利亚第一个骨库设施的运行是成功的。通过提高公众和外科医生对同种异体骨移植的可用性和安全性的认识,可以克服这些挑战。
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来源期刊
Pan African Medical Journal
Pan African Medical Journal PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
1.80
自引率
0.00%
发文量
691
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