Infertility - a Great Challenge of the Past, Present, and Future.

Ivana Erceg Ivkosic, Jana Mesic, Rajko Fures, Zlatko Hrgovic, Luka Bulic, Eva Brenner, Vesna Cosic, Blazenka Miskic, Dinko Kolaric
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Abstract

Background: The Infertility refers to the inability of couples to conceive after 12 months of regular, unprotected sexual intercourse. The incidence of infertility is increasing and is estimated to be 8-12%, or even up to 20%. Primarily, it involves organic causes, but the psychological aspect is not excluded.

Objective: The aim of this article was to discrabe the observing of various causes of infertility.

Methods: Authors used, as sources, published relevant facts in the articles deposited in important scientific indexed databases Medline, Scopus, PubMed Central, Hinari, etc. to write this review.

Results and discussion: The diagnosis of female infertility involves a detailed medical history, laboratory tests, hormonal evaluation, and imaging studies such as ultrasound and eventually hysteroscopy and laparoscopy. Advances in genetic testing have deepened our understanding of infertility origins in both genders. Sperm analysis is pivotal for diagnosing male infertility. Infertility treatment includes identifying causes and applying various therapies, including conservative surgical, and assisted reproductive technology (ART).

Conclusion: The currently used ART methods include ovulation tracking with planned intercourse, insemination and in vitro fertilization (IVF).

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不孕不育——过去、现在和未来的巨大挑战。
背景:不孕症是指夫妇在经过12个月的定期、无保护的性交后仍不能怀孕。不孕症的发病率正在增加,估计为8-12%,甚至高达20%。它主要涉及机体原因,但也不排除心理方面的原因。目的:探讨不孕不育各种病因的观察方法。方法:作者以重要科学索引数据库Medline、Scopus、PubMed Central、Hinari等收录的文章为来源,发表相关事实撰写本综述。结果和讨论:女性不孕症的诊断包括详细的病史、实验室检查、激素评估和影像学检查,如超声和最终的宫腔镜和腹腔镜检查。基因检测的进步加深了我们对男女不孕症起源的理解。精子分析是诊断男性不育症的关键。不孕症的治疗包括确定病因和应用各种疗法,包括保守手术和辅助生殖技术(ART)。结论:目前使用的ART方法包括计划性交、人工授精和体外受精(IVF)。
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