Chitosan Nanoparticles: A Promising Candidate in Wound Healing.

The international journal of lower extremity wounds Pub Date : 2025-03-17 DOI:10.1177/15347346251325057

Masoumeh Askari, Amirhesam Keshavarz Zarjani, Ali Sayyahi, Raziye Badpa, Ali Naghizadeh

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Abstract

The wound healing process is really interesting, dynamic, and complex, captivating researchers for a long time. With the growing worldwide concern regarding the prevalence of wounds and the associated healthcare challenges, efforts to expedite this natural process have intensified. Fortunately, with a particular focus on improving wound dressings, significant advancements have been made in wound care management including using of nanoparticle-based delivery systems. These nanoparticles, similar to molecular messengers, purchase vast promise for revolutionizing wound treatment. Among them, chitosan nanoparticles stand out as remarkable candidates. Their safety profile, biocompatibility, and bioactivity make them particularly appealing for wound care. In this article, we will delve into the intricacies of wound healing and then discuss the wound-healing properties of chitosan nanoparticles, supported by comprehensive study results. Current evidence highlights the wound-healing effects of chitosan nanoparticles, which can be considered independent agents for wound management. In conclusion, the utilization of chitosan nanoparticles for wound healing presents significant opportunities and potential.Graphical abstract [Formula: see text].

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