Chitosan Nanoparticles: A Promising Candidate in Wound Healing.

Masoumeh Askari, Amirhesam Keshavarz Zarjani, Ali Sayyahi, Raziye Badpa, Ali Naghizadeh
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Abstract

The wound healing process is really interesting, dynamic, and complex, captivating researchers for a long time. With the growing worldwide concern regarding the prevalence of wounds and the associated healthcare challenges, efforts to expedite this natural process have intensified. Fortunately, with a particular focus on improving wound dressings, significant advancements have been made in wound care management including using of nanoparticle-based delivery systems. These nanoparticles, similar to molecular messengers, purchase vast promise for revolutionizing wound treatment. Among them, chitosan nanoparticles stand out as remarkable candidates. Their safety profile, biocompatibility, and bioactivity make them particularly appealing for wound care. In this article, we will delve into the intricacies of wound healing and then discuss the wound-healing properties of chitosan nanoparticles, supported by comprehensive study results. Current evidence highlights the wound-healing effects of chitosan nanoparticles, which can be considered independent agents for wound management. In conclusion, the utilization of chitosan nanoparticles for wound healing presents significant opportunities and potential.Graphical abstract [Formula: see text].

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壳聚糖纳米颗粒:伤口愈合的有希望的候选者。
伤口愈合过程非常有趣、动态、复杂,长期以来一直吸引着研究人员。随着世界范围内对伤口流行和相关医疗保健挑战的日益关注,加快这一自然过程的努力已经加强。幸运的是,随着对伤口敷料改进的特别关注,在伤口护理管理方面取得了重大进展,包括使用基于纳米颗粒的输送系统。这些纳米颗粒,类似于分子信使,为革新伤口治疗带来了巨大的希望。其中,壳聚糖纳米颗粒是最引人注目的候选者。它们的安全性、生物相容性和生物活性使它们对伤口护理特别有吸引力。在本文中,我们将深入研究伤口愈合的复杂性,然后在综合研究结果的支持下讨论壳聚糖纳米颗粒的伤口愈合性能。目前的证据强调了壳聚糖纳米颗粒的伤口愈合作用,它可以被认为是伤口管理的独立代理。综上所述,壳聚糖纳米颗粒在伤口愈合中的应用具有重要的机会和潜力。图形摘要[公式:见正文]。
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