Global, regional, and national burdens of fracture in children and adolescents from 1990 to 2019.

IF 3.6 2区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH BMC Public Health Pub Date : 2025-03-19 DOI:10.1186/s12889-025-21958-3

Song Chen, Qingshuang Zhang, Zhibin Ouyang, Yuwei Ning, Juan Zheng, Shunyou Chen

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Abstract

Background: Fractures in children and adolescents(FCA) represent a significant public health concern.This underlines the essential need for comprehensive research into the global burden of disease related to FCA.

Objective: To examine the trajectories of fracture rates and disability-adjusted life years (DALYs) in children and adolescents, as well as to identify contributing risk factors for fracture-associated DALYs between 1990 and 2019.

Methods: This cross-sectional analysis utilized data from the Global Burden of Diseases 2019 (GBD 2019) study. It included individuals with Fracture of Childhood Age (FCA) ranging from 5 to 14 years.

Results: In 2019, there were 33,646,042 incident cases of FCA were reported worldwide. South Asia exhibited the highest number of new cases (8,270,826) and DALYs (190,124 life years) in 2019, accounting for approximately one-fourth of the global data. From 1990 to 2019, the age-standardized incidence slight decreased by 21.19% and DALYs decreased by 28.99% globally. Fractures involving the radius and/r ulna (19.88%) rank as the top most prevalent FCA. Panel models analysis has pinpointed growth in adjusted national income (coefficient B 3.50, p-value 0.02) and per capita adjusted national income (coefficient B 3.48, p-value 0.03) as significant predictors of the worldwide DALYs associated with FCA.

Conclusion: From 1990 to 2019, the burden of FCA exhibited a notable downward trend. However, in low SDI regions such as South Asia, the burden remains substantial. It was found that national income is a risk factor for FCA-associated DALYs, highlighting the need for policies and resources directed towards FCA alongside economic development.

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1990年至2019年全球、区域和国家儿童和青少年骨折负担。

背景：儿童和青少年骨折（FCA）是一个重要的公共卫生问题。这强调了对与FCA有关的全球疾病负担进行全面研究的必要性。目的：研究1990年至2019年间儿童和青少年骨折率和伤残调整生命年（DALYs）的变化轨迹，并确定与骨折相关的DALYs的危险因素。方法：本横断面分析利用了2019年全球疾病负担（GBD 2019）研究的数据。它包括5至14岁的儿童期骨折（FCA）患者。结果：2019年，全球共报告FCA事件33,646,042例。2019年，南亚的新发病例（8,270,826）和伤残调整生命年（190,124生命年）数量最多，约占全球数据的四分之一。从1990年到2019年，全球年龄标准化发病率略有下降21.19%，DALYs下降28.99%。累及桡骨和尺骨的骨折（19.88%）是最常见的FCA。面板模型分析指出，调整后国民收入（系数b3.50， p值0.02）和人均调整后国民收入（系数b3.48， p值0.03）的增长是与FCA相关的全球DALYs的重要预测因子。结论：1990 - 2019年，FCA负担呈明显下降趋势。然而，在低SDI区域，如南亚，负担仍然很大。研究发现，国民收入是与FCA相关的DALYs的风险因素，这突出了在经济发展的同时，针对FCA的政策和资源的需求。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BMC Public Health 医学-公共卫生、环境卫生与职业卫生

CiteScore

6.50

自引率

4.40%

发文量

2108

审稿时长

1 months

期刊介绍： BMC Public Health is an open access, peer-reviewed journal that considers articles on the epidemiology of disease and the understanding of all aspects of public health. The journal has a special focus on the social determinants of health, the environmental, behavioral, and occupational correlates of health and disease, and the impact of health policies, practices and interventions on the community.