Association Between Incorrect Use of Pre- and Post-Exposure Prophylaxis and HIV infection Among Men Who Have Sex with Men - Shenzhen City, Guangdong Province, China, 2021-2023.

IF 2.9 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH 中国疾病预防控制中心周报 Pub Date : 2025-02-21 DOI:10.46234/ccdcw2025.044

Zijie Yang, Jiachun Chen, Lan Wei, Delei Dai, Hu Tang, Yan Zhang, Wei Xie, Shaochu Liu, Wei Tan, Xiangdong Shi, Chenli Zheng, Xiaohong Yuan, Zhongliang Xu, Wei Ye, Jin Zhao

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Abstract

What is already known about this topic?: Preexposure prophylaxis (PrEP) and postexposure prophylaxis (PEP) have been proven effective in preventing human immunodeficiency virus (HIV) transmission.

What is added by this report?: Men who have sex with men (MSM) who incorrectly used PrEP/PEP demonstrated higher HIV positivity rates compared to both correct users and non-users. Since PrEP/PEP users are more likely to engage in unprotected anal intercourse (UAI), incorrect use of these prophylactic measures may constitute a significant risk factor for HIV transmission among MSM.

What are the implications for public health practice?: It is crucial to implement strategies that guide MSM toward correct PrEP/PEP utilization while emphasizing that these prophylactic measures should not be considered substitutes for condom use.

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不正确使用暴露前和暴露后预防与男男性行为者艾滋病毒感染的关系——中国广东省深圳市，2021-2023

关于这个话题我们已经知道了什么？暴露前预防（PrEP）和暴露后预防（PEP）已被证明对预防人类免疫缺陷病毒（HIV）传播有效。这份报告增加了什么内容？与正确使用PrEP/PEP者和未使用者相比，不正确使用PrEP/PEP的男男性行为者（MSM）显示出更高的艾滋病毒阳性率。由于PrEP/PEP使用者更有可能进行无保护肛交（UAI），不正确使用这些预防措施可能构成男男性接触者中艾滋病毒传播的重要危险因素。这对公共卫生实践有什么影响？实施指导男男性行为者正确使用PrEP/PEP的策略是至关重要的，同时强调这些预防措施不应被视为避孕套使用的替代品。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

中国疾病预防控制中心周报

CiteScore

5.90

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0.00%

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