Nickel(II)-Catalyzed Oxidative Homocoupling of Terminal Alkynes

IF 2.7 3区 化学 Q2 CHEMISTRY, ORGANIC European Journal of Organic Chemistry Pub Date : 2025-03-20 DOI:10.1002/ejoc.202500207
Luying Cui, Kai Yang, Yingfan Yang, Daofan Ma, Xiangwei Ren, Guangwei Wang
{"title":"Nickel(II)-Catalyzed Oxidative Homocoupling of Terminal Alkynes","authors":"Luying Cui,&nbsp;Kai Yang,&nbsp;Yingfan Yang,&nbsp;Daofan Ma,&nbsp;Xiangwei Ren,&nbsp;Guangwei Wang","doi":"10.1002/ejoc.202500207","DOIUrl":null,"url":null,"abstract":"<p>The homocoupling of terminal alkynes is a key approach for constructing 1,3-diynes, typically relying on copper-based bimetallic systems. Herein, a catalytic system is developed based on nickel chloride, using 1,10-phenanthroline as the ligand and air as the oxidant, which successfully enables the homocoupling reactions of various terminal alkynes. This reaction is characterized by cheap and stable NiCl<sub>2</sub> as catalyst, mild reaction conditions, and excellent functional group compatibility, demonstrating great potential for practical applications.</p>","PeriodicalId":167,"journal":{"name":"European Journal of Organic Chemistry","volume":"28 22","pages":""},"PeriodicalIF":2.7000,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Organic Chemistry","FirstCategoryId":"92","ListUrlMain":"https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/ejoc.202500207","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0

Abstract

The homocoupling of terminal alkynes is a key approach for constructing 1,3-diynes, typically relying on copper-based bimetallic systems. Herein, a catalytic system is developed based on nickel chloride, using 1,10-phenanthroline as the ligand and air as the oxidant, which successfully enables the homocoupling reactions of various terminal alkynes. This reaction is characterized by cheap and stable NiCl2 as catalyst, mild reaction conditions, and excellent functional group compatibility, demonstrating great potential for practical applications.

Abstract Image

Abstract Image

Abstract Image

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
镍(II)催化末端炔的氧化均偶联
末端炔的均偶联是构建1,3-二炔的关键方法,通常依赖于铜基双金属体系。本文以1,10-菲罗啉为配体,以空气为氧化剂,开发了一种基于氯化镍的催化体系,成功地实现了多种末端炔的均偶联反应。该反应具有催化剂NiCl2便宜稳定、反应条件温和、官能团相容性好等特点,具有很大的实际应用潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
CiteScore
5.40
自引率
3.60%
发文量
752
审稿时长
1 months
期刊介绍: The European Journal of Organic Chemistry (2019 ISI Impact Factor 2.889) publishes Full Papers, Communications, and Minireviews from the entire spectrum of synthetic organic, bioorganic and physical-organic chemistry. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies. The following journals have been merged to form two leading journals, the European Journal of Organic Chemistry and the European Journal of Inorganic Chemistry: Liebigs Annalen Bulletin des Sociétés Chimiques Belges Bulletin de la Société Chimique de France Gazzetta Chimica Italiana Recueil des Travaux Chimiques des Pays-Bas Anales de Química Chimika Chronika Revista Portuguesa de Química ACH—Models in Chemistry Polish Journal of Chemistry.
期刊最新文献
Synthesis and Applications of Functionalized Dibenzothiophene S,S‐Dioxides in Optoelectronics and Bioimaging The Difluorinative Acetonylation of Imidazopyridine Using Acetophenone and Selectfluor Recent Advances in Tandem CH Activation and Named Reactions Toward Structurally Diverse Small‐Molecule Heterocycles: Synergistic Effects and Mechanistic Insights Electrochemical Dehydration of Carboxamides to Their Nitriles Facile Preparation Methods for Triarylmethyl-Type Stable Luminescent Diradicals and Higher Multiradicals
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1