Unlocking the potential of Radix Astragali and its active ingredients in gastric ulcer therapy

IF 1.3 3区 医学 Q3 CHEMISTRY, APPLIED Journal of Asian Natural Products Research Pub Date : 2025-11-02 DOI:10.1080/10286020.2025.2475475
Pei-Pei Zhang , Jing-Ni Tang , Bo-Yu Xiang , Liang Li , Meng-Zhou Xie , Hao-Yu Qu
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Abstract

We studied the protective effects of Radix Astragali (RA) on gastric ulcer (GU). A literature search was conducted using databases from Web of Science, PubMed, Springer, ScienceDirect, Science Direct Chinese National Knowledge Infrastructure (CNKI), and Wanfang. The inclusion criteria for this study were limited to reports on the effects of RA, AS-IV, cycloastragenol, astragalus polysaccharide (APS), and astragalosides (AST) in the treatment of gastric ulcers. Any studies involving gastric lesions that were precancerous or cancerous were eliminated. The search period was from database inception through June 2024. The results suggested RA hold promiseas potential novel therapeutics for the therapy of GU.
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发掘黄芪及其有效成分在胃溃疡治疗中的潜力。
研究了黄芪(RA)对胃溃疡的保护作用。使用Web of Science、PubMed、b施普林格、ScienceDirect、ScienceDirect Chinese National Knowledge Infrastructure (CNKI)和万方数据库进行文献检索。本研究的纳入标准仅限于RA、AS-IV、环黄芪醇、黄芪多糖(APS)和黄芪甲苷(AST)治疗胃溃疡的疗效。任何涉及癌前或癌性胃病变的研究都被排除。搜索周期从数据库建立到2024年6月。结果表明,RA有望成为治疗GU的潜在新疗法。
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来源期刊
CiteScore
3.20
自引率
5.90%
发文量
47
审稿时长
2.3 months
期刊介绍: The Journal of Asian Natural Products Research (JANPR) publishes chemical and pharmaceutical studies in the English language in the field of natural product research on Asian ethnic medicine. The journal publishes work from scientists in Asian countries, e.g. China, Japan, Korea and India, including contributions from other countries concerning natural products of Asia. The journal is chemistry-orientated. Major fields covered are: isolation and structural elucidation of natural constituents (including those for non-medical uses), synthesis and transformation (including biosynthesis and biotransformation) of natural products, pharmacognosy, and allied topics. Biological evaluation of crude extracts are acceptable only as supporting data for pure isolates with well-characterized structures. All published research articles in this journal have undergone rigorous peer review, based on initial editor screening and anonymized refereeing by at least two expert referees.
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