Healthcare-associated infections and antimicrobial use: the third point prevalence survey on 42 acute care hospitals in Piedmont, Italy, 2022.

IF 3.8 3区医学 Q2 INFECTIOUS DISEASES American journal of infection control Pub Date : 2025-03-18 DOI:10.1016/j.ajic.2025.03.019

Antonino Russotto, Claudia Gastaldo, Stefania Di Giacomo, Stefano Bazzolo, Dario Gamba, Carla Maria Zotti, Costanza Vicentini

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Abstract

Background: Healthcare-associated infections (HAIs), antibiotic use (AMU) and antimicrobial resistance (AMR) are critical indicators of healthcare quality and antimicrobial stewardship. Point prevalence surveys provide essential data for optimizing infection prevention and control (IPC) strategies.

Objective: To describe the prevalence of HAIs, AMU and AMR across hospital levels and wards in Piedmont, Italy, highlighting associations with hospital complexity and patient care characteristics.

Methods: Data included hospital charatheristics, demographics, HAI, AMU, AMR, and clinical characteristics. Prevalence ratios (PRs) were calculated to compare rates across subgroups.

Results: The prevalence of HAIs was 8%, with increased invasive device usage contributed (PR 1.71, 95% CI 1.64-1.78). AMU prevalence decreased to 40% from 42.8% in 2016. Trends in antibiotic use aligned with the "Italian National Action Plan to contrast AMR" (PNCAR) goals, showing reduced fluoroquinolone use and increased amoxicillin prescriptions. AMR trends showed improvements in oxacillin-resistant Staphylococcus aureus and cephalosporin-resistant Escherichia coli and Klebsiella pneumoniae.

Discussion and conclusion: The results highlight the critical importance of sustained investment in IPC measures and robust antimicrobial stewardship programs. Addressing these key areas will be essential to mitigating the burden of HAIs, promoting the judicious use of antibiotics, and ultimately enhancing patient care and outcomes across the region.

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来源期刊

American journal of infection control 医学-传染病学

CiteScore

7.40

自引率

4.10%

发文量

479

审稿时长

24 days

期刊介绍： AJIC covers key topics and issues in infection control and epidemiology. Infection control professionals, including physicians, nurses, and epidemiologists, rely on AJIC for peer-reviewed articles covering clinical topics as well as original research. As the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC)

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Healthcare-associated infections and antimicrobial use: the third point prevalence survey on 42 acute care hospitals in Piedmont, Italy, 2022. Table of Contents Editorial Board APIC Masthead Information for Readers